2-[(6-Methoxy-9H-purin-9-yl)methyl]-1-azabicyclo[2.2.2]octan-3-one | 586390-59-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: 2-[(6-Methoxy-9H-purin-9-yl)methyl]-1-azabicyclo[2.2.2]octan-3-one
• 英文别名: 2-[(6-methoxypurin-9-yl)methyl]-1-azabicyclo[2.2.2]octan-3-one
• CAS: 586390-59-2
• 化学式: C₁₄H₁₇N₅O₂
• 分子量: 287.32
• InChiKey: DCCARQLVOIEBCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  73.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• AQUEOUS SOLUTION COMPRISING 3 - QUINUCLIDINONES FOR THE TREATMENT HYPERPROLIFERATIVE, AUTOIMMUNE AND HEART DISEASE
  申请人：Bystrom Styrbjorn

  公开号：US20120289503A1

  公开（公告）日：2012-11-15

  A liquid composition that is an aqueous solution of a compound of formula (I), wherein the aqueous solution has a pH from about 3.0 to about 5.0. The liquid composition may be used in the treatment of a disorder selected from hyperproliferative diseases, autoimmune diseases and heart diseases.
• US7659278B2
  申请人：——

  公开号：US7659278B2

  公开（公告）日：2010-02-09
• US9061016B2
  申请人：——

  公开号：US9061016B2

  公开（公告）日：2015-06-23
• [EN] METHOD AND COMPOSITION<br/>[FR] PROCÉDÉ ET COMPOSITION
  申请人：APREA AB

  公开号：WO2011089234A2

  公开（公告）日：2011-07-28

  A liquid composition that is an aqueous solution of a compound of formula (I), wherein the aqueous solution has a pH from about 3.0 to about 5.0. The liquid composition may be used in the treatment of a disorder selected from hyperproliferative diseases, autoimmune diseases and heart diseases.