(1R,5R)-6,6-Dimethyl-3-[1-naphthalen-1-yl-meth-(E)-ylidene]-bicyclo[3.1.1]heptan-2-one | 188851-28-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (1R,5R)-6,6-Dimethyl-3-[1-naphthalen-1-yl-meth-(E)-ylidene]-bicyclo[3.1.1]heptan-2-one
• CAS: 188851-28-7
• 化学式: C₂₀H₂₀O
• 分子量: 276.378
• InChiKey: DYHORTLUJJHCOA-XVKGOSMNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.86
• 重原子数：
  21.0
• 可旋转键数：
  1.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  (1R,5R)-6,6-Dimethyl-3-[1-naphthalen-1-yl-meth-(E)-ylidene]-bicyclo[3.1.1]heptan-2-one 在 palladium on activated charcoal 氢气 作用下， 以 乙酸乙酯 为溶剂， 生成
  参考文献：
  名称：

  Synthesis and structural determination of new chiral auxiliaries derived from (−)-β-pinene

  摘要：

  New chiral auxiliaries, alcohols syn-11a,e and syn-12a,e, were readily synthesized in a stereoselective manner from (-)-beta-pinene. Their stereochemical determinations have been made on the basis of nOe experiments. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0957-4166(96)00523-x
• 作为产物：
  描述：

  beta-pinene 、 alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 、 二甲基硫 、 臭氧 作用下， 反应 42.0h， 生成 (1R,5R)-6,6-Dimethyl-3-[1-naphthalen-1-yl-meth-(E)-ylidene]-bicyclo[3.1.1]heptan-2-one
  参考文献：
  名称：

  Synthesis and structural determination of new chiral auxiliaries derived from (−)-β-pinene

  摘要：

  New chiral auxiliaries, alcohols syn-11a,e and syn-12a,e, were readily synthesized in a stereoselective manner from (-)-beta-pinene. Their stereochemical determinations have been made on the basis of nOe experiments. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0957-4166(96)00523-x