α-1-Naphthalenyl-N-phenyl-1-naphthalenemethanamine | 135505-59-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: α-1-Naphthalenyl-N-phenyl-1-naphthalenemethanamine
• 英文别名: N-(dinaphthalen-1-ylmethyl)aniline
• CAS: 135505-59-8
• 化学式: C₂₇H₂₁N
• 分子量: 359.47
• InChiKey: RCYVOZMRXKOAOI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.19
• 重原子数：
  28.0
• 可旋转键数：
  4.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  12.03
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  [1]naphthylmethylen-aniline 在 sodium 、 N,N-二甲基甲酰胺 作用下， 反应 3.0h， 生成 α-1-Naphthalenyl-N-phenyl-1-naphthalenemethanamine
  参考文献：
  名称：

  Novel synthesis of N,N-diarylarylmethanamines from N-(arylmethylene)arenamines and (arylmethoxy)arenes

  摘要：

  Various N,N-diarylarylmethanamines were synthesized by the reaction of N-(arylmethylene)arenamines with (arylmethoxy)arenes in dimethylformamide solution in the presence of a strong base as a catalyst which is obtained in situ by reacting metallic sodium with this solvent. In general, the reaction may be depicted as the reduction of the imine and addition, on the original imino nitrogen atom, of the aryl group (of the aryloxy moiety) of the ether and presumably oxidation of the arylmethoxy group of the either to its corresponding aldehyde. Side reactions and a proposed reaction mechanism are discussed.

  DOI：

  10.1021/jo00020a032