2-(Aminomethyl)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}benzoic acid | 219640-94-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 2-(Aminomethyl)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}benzoic acid
• 英文别名: 2-(aminomethyl)-3-(9H-fluoren-9-ylmethoxycarbonyl)benzoic acid
• CAS: 219640-94-5
• 化学式: C₂₃H₁₉NO₄
• 分子量: 373.4
• InChiKey: PJLRRGNIWJISPR-UHFFFAOYSA-N

物化性质

• 沸点：
  617.4±43.0 °C(Predicted)
• 密度：
  1.296±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  89.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Facilitated forward chemical genetics using tagged triazine library
  申请人：Chang Young-Tae

  公开号：US20050019831A1

  公开（公告）日：2005-01-27

  A novel tagged triazine library is provided in which three building blocks are prepared separately and assembled orthogonally to yield 1536 highly pure compounds. Each library compound contains a variety of a triethyleneglycol (TG) linker at one of the diversity sites of the triazine scaffold.
• US7749940B2
  申请人：——

  公开号：US7749940B2

  公开（公告）日：2010-07-06
• [EN] FACILITATED FORWARD CHEMICAL GENETICS USING TAGGED TRIAZINE LIBRARY<br/>[FR] GENETIQUE CHIMIQUE FACILITEE VERS L'AVANT UTILISANT UNE BANQUE DE TRIAZINES MARQUEES
  申请人：UNIV NEW YORK

  公开号：WO2004099106A2

  公开（公告）日：2004-11-18

  A novel tagged triazine library is provided in which three building blocks are prepared separately and assembled orthogonally to yield 1536 highly pure compounds. Each library compound contains a variety of a triethyleneglycol (TG) linker t one of the diversity sites of the triazine scaffold.
• [EN] METHODS AND MATERIALS FOR PREPARING ORGANIC COMPOUNDS FROM PRIMARY AMINES<br/>[FR] PROCEDES ET MATERIAUX POUR LA PREPARATION DE COMPOSES ORGANIQUES A PARTIR D'AMINES PRIMAIRES
  申请人：UNIV VIRGINIA

  公开号：WO2007117404A9

  公开（公告）日：2007-11-29

  [EN] Methods are disclosed for the conversion of primary amines to other functional groups. The methods can be used to prepare chiral organic compounds, including organic alcohols and organic halides. The methods can be carried out by treating a primary amine with an activating agent and a nitrosyl agent to produce the transformed compound along with nitrous oxide.
  [FR] L'invention concerne des procédés de conversion d'amines primaires en autres groupements fonctionnels. Les procédés peuvent être utilisés pour préparer des composés organiques chiraux, y compris des alcools organiques et des halogénures organiques. Les procédés peuvent être réalisés en traitant une amine primaire avec un agent d'activation et un agent nitrosyle pour obtenir le composé transformé ainsi que de l'oxyde nitreux.