2,3-Dihydro-1H-isoindole-1,3-diol | 342402-85-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2,3-Dihydro-1H-isoindole-1,3-diol
• 英文别名: Isoindoline-1,3-diol
• CAS: 342402-85-1
• 化学式: C₈H₉NO₂
• 分子量: 151.165
• InChiKey: CJKLUMPOZDSVKY-UHFFFAOYSA-N

物化性质

• 沸点：
  365.1±42.0 °C(Predicted)
• 密度：
  1.392±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  52.5
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  邻苯二甲醛 、 氨 、 乙醚 生成 2,3-Dihydro-1H-isoindole-1,3-diol
  参考文献：
  名称：

  DOMINH T.; JOHNSON A. L.; JONES J. E.; SENISE P. P. JR., J. ORG. CHEM. , 1977, 42, 26, 4217-4221

  摘要：

  DOI：

文献信息

• Test strip for simultaneous detection of a plurality of analytes
  申请人：——

  公开号：US20020086435A1

  公开（公告）日：2002-07-04

  A test strip for simultaneously measuring a plurality of analytes in blood or other fluids comprising a plurality of reagent pads containing reagents specific to particular analytes located on a support. Each reagent pad is covered and in close contact with a sample distributing layer and an optional blood filtering layer. Color produced by analytes in the sample is viewed through apertures in the support. The colors of the pads are read simultaneously with an instrument such as a reflectance meter containing individual LED's as light sources for each reagent pad. The intensity of the color of the individual pad can be used to detect semi-quantitative or quantitative concentration of analytes in a sample on site, allowing for quick communication of results to a remote site by electronic means.

  一种同时测量血液或其他液体中多种分析物的试纸，包括多个试剂垫，试剂垫上有特定分析物的特异性试剂。每个试剂垫都覆盖在样品分布层和可选的血液过滤层上，并与之紧密接触。样品中的分析物产生的颜色可通过支架上的小孔观察到。试剂垫的颜色可通过仪器同时读取，如反射率仪，该仪器包含单个 LED 作为每个试剂垫的光源。单个试剂垫的颜色强度可用于现场检测样品中分析物的半定量或定量浓度，并通过电子手段将结果快速传送到远程站点。
• Test device for simultaneous measurement of multiple analytes in a single sample
  申请人：Gupta K. Surendra

  公开号：US20050214161A1

  公开（公告）日：2005-09-29

  The invention consists of a test device for simultaneous measurement of multiple analytes in one sample where the liquid sample is applied to a matrix at the central area of the device which is connected to multiple arms, and each of the arms contains specific reagents in dry form for measurement of a particular analyte. The sample travels from the center uniformly and quickly to the reagent site on each arm and produces a measurable signal that may be a change in electrical charge or current, fluorescence, or, preferably, color. A color change can be detected visually or measured quantitatively using a suitable reflectance meter. The sample may be a small amount of whole blood obtained e.g., from a finger puncture or it may be urine, saliva, any other bodily fluid, environmental water, or any other fluid upon which rapid, simultaneous testing of levels of different components is desired. According to the invention, a disease specific panel for kidney, liver, heart, lipid disorders or for early detection of dysfunction of general health can be performed at or near the patients' site and can provide instant results. Similarly, rapid simultaneous testing of water samples is desirable under many circumstances.

  本发明包括一种测试装置，用于同时测量一个样品中的多种分析物，其中液体样品被施加到装置中心区域的基质上，该基质连接到多个臂上，每个臂上都装有特定的干试剂，用于测量特定的分析物。样品从中心均匀而快速地流向每个臂上的试剂点，并产生可测量的信号，该信号可能是电荷或电流、荧光的变化，或者最好是颜色的变化。颜色的变化可以通过视觉检测，也可以使用合适的反射仪进行定量测量。样品可以是少量的全血，例如从手指穿刺获得的全血，也可以是尿液、唾液、任何其他体液、环境水或任何其他需要快速、同步检测不同成分水平的液体。根据本发明，针对肾脏、肝脏、心脏、血脂紊乱的疾病特异性检测，或针对一般健康功能障碍的早期检测，均可在患者现场或附近进行，并可提供即时结果。同样，在许多情况下，也需要对水样进行快速同步检测。
• TEST STRIP FOR SIMULTANEOUS DETECTION OF A PLURALITY OF ANALYTES
  申请人：Inverness Medical Switzerland GmbH

  公开号：EP1356282B1

  公开（公告）日：2007-06-20
• EP1356282A4
  申请人：——

  公开号：EP1356282A4

  公开（公告）日：2005-04-06
• US6524864B2
  申请人：——

  公开号：US6524864B2

  公开（公告）日：2003-02-25