(+/-)-2-Ethyl-tetrahydrofuranol-(2) | 89534-32-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: (+/-)-2-Ethyl-tetrahydrofuranol-(2)
• 英文别名: 2-Ethyloxolan-2-ol
• CAS: 89534-32-7
• 化学式: C₆H₁₂O₂
• 分子量: 116.16
• InChiKey: ZEAPATDHUJQDGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS
  申请人：Aissaoui Hamed

  公开号：US20110224210A1

  公开（公告）日：2011-09-15

  The invention relates to novel bis-amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria.

  这项发明涉及新型双酰胺衍生物及其在制备药物组合物中作为活性成分的用途。该发明还涉及相关方面，包括含有这些化合物中的一个或多个的药物组合物以及它们作为治疗或预防原虫感染的药物，尤其是疟疾的用途。
• SYNTHESIS OF R-GLUCOSIDES, SUGAR ALCOHOLS, REDUCED SUGAR ALCOHOLS, AND FURAN DERIVATIVES OF REDUCED SUGAR ALCOHOLS
  申请人：Archer-Daniels-Midland Company

  公开号：EP3129341A1

  公开（公告）日：2017-02-15
• [EN] SYNTHESIS OF R-GLUCOSIDES, SUGAR ALCOHOLS, REDUCED SUGAR ALCOHOLS, AND FURAN DERIVATIVES OF REDUCED SUGAR ALCOHOLS<br/>[FR] SYNTHÈSE DE R-GLUCOSIDES, SUCRES-ALCOOLS, SUCRES-ALCOOLS RÉDUITS ET DÉRIVÉS DE FURANE DE SUCRES-ALCOOLS RÉDUITS
  申请人：ARCHER DANIELS MIDLAND CO

  公开号：WO2015156803A1

  公开（公告）日：2015-10-15

  Disclosed herein are methods for synthesizing 1,2,5,6-hexanetetrol (HTO), 1,6 hexanediol (HDO) and other reduced polyols from C5 and C6 sugar alcohols or R glycosides. The methods include contacting the sugar alcohol or R-glycoside with a copper catalyst, most desirably a Raney copper catalyst with hydrogen for a time, temperature and pressure sufficient to form reduced polyols having 2 to 3 fewer hydoxy groups than the starting material. When the starting compound is a C6 sugar alcohol such as sorbitol or R-glycoside of a C6 sugar such as methyl glucoside, the predominant product is HTO. The same catalyst can be used to further reduce the HTO to HDO.