1-[8-(Trifluoromethyl)-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl]propan-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 香豆素
• 英文名称: 1-[8-(Trifluoromethyl)-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl]propan-2-amine
• 英文别名: 1-[4-(trifluoromethyl)-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-8-yl]propan-2-amine
• 化学式: C₁₄H₁₆F₃NO₂
• 分子量: 287.28
• InChiKey: KMWGSFWAZUVTCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• COMPOSITIONS AND METHODS TO REDUCE PATHOGENESIS
  申请人：The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College

  公开号：US20200078335A1

  公开（公告）日：2020-03-12

  This invention is directed to compositions, methods and kits for ameliorating or reducing pathogenesis of a disease by administering to a subject a serotonin receptor agonist.
• COMPOSITIONS AND METHODS FOR TREATING OCULAR PATHOLOGIES
  申请人：The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College

  公开号：US20200330405A1

  公开（公告）日：2020-10-22

  This invention features compositions, methods, and kits for treating conditions associated with pathological ocular neovascularization, reducing scarring in the eye, treating dry eye, treating macular degeneration, and treating keratitis by administering a serotonin receptor agonist.