4-(2-Methylpropyl)oxane-4-carboxylic acid | 1385696-76-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 4-(2-Methylpropyl)oxane-4-carboxylic acid
• CAS: 1385696-76-3
• 化学式: C₁₀H₁₈O₃
• 分子量: 186.25
• InChiKey: XLHPBFPOLSJCHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• (R)-4-((4-((4-(TETRAHYDROFURAN-3-YLOXY)BENZO[D]ISOXAZOL-3-YLOXY)METHYL)PIPERIDIN-1-YL)METHYL)TETRAHYDRO-2H-PYRAN-4-OL, A PARTIAL AGONIST OF 5-HT4 RECEPTORS
  申请人：Waizumi Nobuaki

  公开号：US20120041026A1

  公开（公告）日：2012-02-16

  (R)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol and its use in treating neurodegenerative disorders, is described herein.

  本文描述了(R)-4-((4-((4-(四氢呋喃-3-氧基)苯并[d]异噁唑-3-氧基)甲基)哌啶-1-基)甲基)四氢-2H-吡喃-4-醇及其用于治疗神经退行性疾病的用途。
• INDOLINYL SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE
  申请人：Lycera Corporation

  公开号：US20200207726A1

  公开（公告）日：2020-07-02

  The invention provides aryl indolinyl sulfonamide and related compounds, pharmaceutical compositions, methods of promoting RORγ activity and/or increasing the amount of IL-17 in a subject, and therapeutic uses of the indolinyl sulfonamide and related compounds, such as treating medical conditions in which activation of immune response is beneficial.
• US8178681B2
  申请人：——

  公开号：US8178681B2

  公开（公告）日：2012-05-15
• US8367666B2
  申请人：——

  公开号：US8367666B2

  公开（公告）日：2013-02-05