(1S,5R)-5-(tert-Butyl-diphenyl-silanyloxy)-3-[2-[(R)-1-[(S)-2-(2-hydroxy-2-methyl-propoxy)-1-methyl-ethyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexanol | 137832-50-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (1S,5R)-5-(tert-Butyl-diphenyl-silanyloxy)-3-[2-[(R)-1-[(S)-2-(2-hydroxy-2-methyl-propoxy)-1-methyl-ethyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexanol
• CAS: 137832-50-9
• 化学式: C₄₂H₆₀O₄Si
• 分子量: 657.022
• InChiKey: CRJWMLRTSMTXFD-OYZRREDESA-N

反应信息

• 作为反应物：
  描述：

  (1S,5R)-5-(tert-Butyl-diphenyl-silanyloxy)-3-[2-[(R)-1-[(S)-2-(2-hydroxy-2-methyl-propoxy)-1-methyl-ethyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexanol 以65%的产率得到(4S,6R)-6-(tert-Butyl-diphenyl-silanyloxy)-8-[2-[(R)-1-[(S)-2-(2-hydroxy-2-methyl-propoxy)-1-methyl-ethyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-spiro[2.5]octan-4-ol
  参考文献：
  名称：

  Synthesis of 23-oxa-calcitriol derivatives

  摘要：

  A convenient synthetic strategy leading to 23-oxa-calcitriol and 23-oxa-10,19-methylene-calcitriol is disclosed.

  DOI：

  10.1016/s0040-4039(00)93431-2
• 作为产物：
  描述：

  1-((S)-2-{(R)-4-[2-[(3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propoxy)-2-methyl-propan-2-ol 在 盐酸 作用下， 以 甲醇 为溶剂， 生成 (1S,5R)-5-(tert-Butyl-diphenyl-silanyloxy)-3-[2-[(R)-1-[(S)-2-(2-hydroxy-2-methyl-propoxy)-1-methyl-ethyl]-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexanol
  参考文献：
  名称：

  Synthesis of 23-oxa-calcitriol derivatives

  摘要：

  A convenient synthetic strategy leading to 23-oxa-calcitriol and 23-oxa-10,19-methylene-calcitriol is disclosed.

  DOI：

  10.1016/s0040-4039(00)93431-2