[12-(2-Hydroxy-phenyl)-1-phenyl-dodecyl]-carbamic acid tert-butyl ester | 141920-43-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: [12-(2-Hydroxy-phenyl)-1-phenyl-dodecyl]-carbamic acid tert-butyl ester
• CAS: 141920-43-6
• 化学式: C₂₉H₄₃NO₃
• 分子量: 453.665
• InChiKey: BEKVFJAUKLTLLA-UHFFFAOYSA-N

物化性质

• 沸点：
  582.4±33.0 °C(Predicted)
• 密度：
  1.026±0.06 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  [12-(2-Hydroxy-phenyl)-1-phenyl-dodecyl]-carbamic acid tert-butyl ester 在 N-甲基咪唑 、 三氟化硼乙醚 、 三氟乙酸 作用下， 以 甲醇 、 二氯甲烷 、 乙酸乙酯 为溶剂， 生成 Acetic acid (4Z,6E)-2-oxo-19-phenyl-azacyclononadeca-4,6-dien-7-yl ester
  参考文献：
  名称：

  Photolactamization: A Novel Synthetic Entry into Large Ring-Sized Lactams

  摘要：

  Diene ketenes smoothly accessible by photochemical ring cleavage of omicron-quinol acetates, in the presence of primary or secondary amines afford the corresponding amides. In an intramolecular version of this reaction macrocyclic lactams of type A are produced, if aminoalkylated omicron-quinol acetates of type C are used as photo reactants. These photo reactants are available on acid mediated removal of the Boc-protecting group from Wessely acetoxylation products of type D, easily formed via compounds of type E from aminoalkylated phenols of type F.

  DOI：

  10.1016/0040-4039(92)88118-o
• 作为产物：
  描述：

  Methanesulfonic acid 12-(2-hydroxy-phenyl)-1-phenyl-dodecyl ester 在 lithium aluminium tetrahydride 、 sodium azide 作用下， 生成 [12-(2-Hydroxy-phenyl)-1-phenyl-dodecyl]-carbamic acid tert-butyl ester
  参考文献：
  名称：

  Photolactamization: A Novel Synthetic Entry into Large Ring-Sized Lactams

  摘要：

  Diene ketenes smoothly accessible by photochemical ring cleavage of omicron-quinol acetates, in the presence of primary or secondary amines afford the corresponding amides. In an intramolecular version of this reaction macrocyclic lactams of type A are produced, if aminoalkylated omicron-quinol acetates of type C are used as photo reactants. These photo reactants are available on acid mediated removal of the Boc-protecting group from Wessely acetoxylation products of type D, easily formed via compounds of type E from aminoalkylated phenols of type F.

  DOI：

  10.1016/0040-4039(92)88118-o