N-Carbamoyl-norbornen-(2)-dicarbonsaeure-(5,6)-imid | 27867-64-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: N-Carbamoyl-norbornen-(2)-dicarbonsaeure-(5,6)-imid
• 英文别名: 1,3-dioxo-1,3,3a,4,7,7a-hexahydro-4,7-methano-isoindole-2-carboxylic acid amide；3,5-Dioxo-4-azatricyclo[5.2.1.02,6]dec-8-ene-4-carboxamide
• CAS: 27867-64-7
• 化学式: C₁₀H₁₀N₂O₃
• 分子量: 206.201
• InChiKey: WNESSQFLPXSQSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  80.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• BRUSH PRODRUGS AND USES THEREOF
  申请人：Massachusetts Institute of Technology

  公开号：US20210386861A1

  公开（公告）日：2021-12-16

  The present disclosure provides, in some aspects, macromonomers of Formula (I), and salts thereof; methods of preparing the macromonomers, and salts thereof; Brush prodrugs (polymers); methods of preparing the Brush prodrugs; compounds of Formula (II); conjugates of Formula (III), and salts thereof; pharmaceutical compositions comprising a Brush prodrug, or a conjugate or a salt thereof; kits comprising: a macromonomer or a salt thereof, a Brush prodrug, a compound, a conjugate or a salt thereof, or a pharmaceutical composition; methods of using the Brush prodrugs, or conjugates or salts thereof; and uses of the Brush prodrugs, and conjugates or salts thereof. These chemical entities may be useful in delivering pharmaceutical agents to a subject or cell.