5-(Methylamino)isoindoline-1,3-dione | 24264-14-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 5-(Methylamino)isoindoline-1,3-dione
• 英文别名: 5-(methylamino)isoindole-1,3-dione
• CAS: 24264-14-0
• 化学式: C₉H₈N₂O₂
• 分子量: 176.17
• InChiKey: QXEKSVJYGUPERB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE
  申请人：Kubota Hideki

  公开号：US20080227785A1

  公开（公告）日：2008-09-18

  This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient. It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dementia, in which the BEC 1 potassium channel is considered to be concerned. Illustratively, it was confirmed by an in vivo test that the BEC 1 potassium channel inhibitor has an action to improve learning disorder. Also, it was found that a compound having 2,4,6-triamino-1,3,5-triazine has a BEC 1 potassium channel inhibitory action.

  本发明涉及一种以BEC 1钾离子通道抑制剂作为活性成分的抗痴呆剂。已经证明，BEC 1钾离子通道抑制剂具有改善学习障碍的作用，并且作为预防或治疗剂是有用的，尤其是对于BEC 1钾离子通道与之相关的疾病，如痴呆症。例如，通过体内试验证实，BEC 1钾离子通道抑制剂具有改善学习障碍的作用。此外，还发现具有2,4,6-三氨基-1,3,5-三嗪的化合物具有BEC 1钾离子通道抑制作用。
• Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof
  申请人：Han Amy Qi

  公开号：US20120009151A1

  公开（公告）日：2012-01-12

  Disclosed herein are novel triazines and related compounds, the synthesis thereof, and compositions, including pharmaceutical compositions, comprising the novel triazines and related compounds. Such novel triazines and related compounds function to inhibit or block entry of viruses of the Flaviviridae family, including Hepatitis C virus (HCV), into cells that are susceptible to virus infection. These compounds are useful for the treatment, therapy and/or prophylaxis of viral diseases and infection, including HCV infection.

  本文披露了新型三嗪及其相关化合物，其合成方法以及包含新型三嗪和相关化合物的组合物，包括药物组合物。这些新型三嗪和相关化合物的功能是抑制或阻止易感染病毒的细胞进入黄病毒科病毒，包括丙型肝炎病毒（HCV）。这些化合物对于治疗、治疗和/或预防病毒性疾病和感染，包括HCV感染，是有用的。
• Neue Monoazopigmente
  申请人：CIBA-GEIGY AG

  公开号：EP0064952A1

  公开（公告）日：1982-11-17

  Verbindungen der Formel worin die Symbole X, Y, R, R1, R2, m und n die in Patentanspruch 1 angegebene Bedeutung haben, eignen sich als hochwertige Pigmente zum Pigmentieren von hochmolekularem organischem Material. Sie zeichnen sich insbesondere durch hohe Licht-, Migrations- und Wetterechtheit aus.

  式中符号 X、Y、R、R1、R2、m 和 n 的含义如权利要求 1 所述，这些化合物可作为高品质颜料，用于高分子有机材料的着色。 它们尤其具有耐光性、耐迁移性和耐候性高的特点。
• COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT
  申请人：Mitsubishi Chemical Corporation

  公开号：EP1867684A1

  公开（公告）日：2007-12-19

  It is to provide a dye for an anisotropic dye film to be formed by a wet system film-forming method, which is achromatic and has high dichroism and a high degree of molecular orientation, an anisotropic dye film containing the dye and a polarizing element employing the film. A dye for an anisotropic dye film to be formed by a wet system film-forming method, of which the free acid form is represented by the following formula (I), a composition for an anisotropic dye film containing the dye, an anisotropic dye film and a polarizing element employing the anisotropic dye film: wherein A11: a (substituted) phenyl group, a (substituted) naphthyl group or a (substituted) aromatic heterocyclic group; B11: a bivalent aromatic hydrocarbon group or aromatic hydrocyclic group; R11, R22: H, OH, a (substituted) alkyl group, a (substituted) phenyl group or a (substituted) acyl group; n': 1 or 2; m: 0 or 1.

  本发明旨在提供一种用于通过湿法成膜系统形成的各向异性染料膜的染料，该染料为消色差染料，具有高二色性和高分子取向性；一种含有该染料的各向异性染料膜；以及一种采用该薄膜的偏振元件。 一种用于通过湿法成膜工艺形成的各向异性染料膜的染料，其游离酸形式由下式（I）表示；一种含有该染料的各向异性染料膜的组合物；一种各向异性染料膜和一种使用该各向异性染料膜的偏光元件： 其中 A11：（取代的）苯基、（取代的）萘基或（取代的）芳香杂环基； B11：二价芳香烃基团或芳香烃环基团； R11、R22：H、OH、（取代的）烷基、（取代的）苯基或（取代的）酰基； n':1或2；m：0或1。
• SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION
  申请人：UNIVERSITY OF KANSAS

  公开号：US20220031661A1

  公开（公告）日：2022-02-03

  The present technology provides compounds of Formula I and related methods for treating a bacterial infection as well as methods for inhibiting interaction of a bacterioferritin and a bacterioferritin-associated ferredoxin.