N-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]-1,1-dimethylethyl}morpholin-4-ylcarboxamide | 507262-90-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: N-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]-1,1-dimethylethyl}morpholin-4-ylcarboxamide
• 英文别名: N-[1-[4-amino-2-(ethoxymethyl)-6,7-dimethylimidazo[4,5-c]pyridin-1-yl]-2-methylpropan-2-yl]morpholine-4-carboxamide
• CAS: 507262-90-0
• 化学式: C₂₀H₃₂N₆O₃
• 分子量: 404.512
• InChiKey: WIJUADBJWJMUGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Urea substituted imidazopyridines
  申请人：3M Innovative Properties Company

  公开号：US20030176458A1

  公开（公告）日：2003-09-18

  Imidazopyridine compounds that contain urea or thiourea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

  在1位点含有脲或硫脲官能团的咪唑吡啶化合物可用作免疫反应改变剂。该发明的化合物和组合物可诱导多种细胞因子的生物合成，在治疗包括病毒性疾病和肿瘤性疾病在内的各种疾病中有用。
• UREA SUBSTITUTED IMIDAZOPYRIDINES
  申请人：3M Innovative Properties Company

  公开号：EP1451186A2

  公开（公告）日：2004-09-01
• US6545017B1
  申请人：——

  公开号：US6545017B1

  公开（公告）日：2003-04-08
• [EN] UREA SUBSTITUTED IMIDAZOPYRIDINES<br/>[FR] IMIDAZOPYRIDINES A SUBSTITUTION UREE
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2003050119A2

  公开（公告）日：2003-06-19

  Imidazopyridine compounds that contain urea or thiourea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.