Octadec-9-enoyl isocyanate | 113952-29-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Octadec-9-enoyl isocyanate
• CAS: 113952-29-7
• 化学式: C₁₉H₃₃NO₂
• 分子量: 307.5
• InChiKey: FQSWVADHNGQZOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  22
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  46.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS
  申请人：Hope Michael J.

  公开号：US20110117125A1

  公开（公告）日：2011-05-19

  The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of specific target protein at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.

  本发明提供了递送治疗剂到细胞的组合物和方法。特别地，这些包括新型脂质和核酸-脂质颗粒，它们提供了核酸的高效封装和封装的核酸在体内细胞中的高效递送。本发明的组合物非常有效，因此可以在相对较低的剂量下有效地降低特定靶蛋白的表达。此外，本发明的组合物和方法比先前在艺术领域中已知的组合物和方法毒性更小，提供更大的治疗指数。
• New 3-alkylthio-2-O-carbamoyl-propane-1.2-diol-1-O-phosphocholines, and processes for their preparation
  申请人：A. Nattermann & Cie. GmbH

  公开号：EP0118090A1

  公开（公告）日：1984-09-12

  The present invention relates to new 3-alkylthio-2-0-carbamoyl-propan-1,2-diol-1-0-phosphocholines of the general formula I and processes for their preparation.

  本发明涉及通式 I 的新 3-烷硫基-2-0-氨基甲酰基-丙-1,2-二醇-1-0-磷酸胆碱及其制备工艺。 及其制备工艺。
• PSEUDOURIDINE DERIVATIVE
  申请人：KATSUNUMA, Nobuhiko

  公开号：EP0266426A1

  公开（公告）日：1988-05-11

  5'-Pseudouridyl N-oleoylcarbamate represented by formula (1). This compound has a physiological activity of remarkably enhancing the activity of glycocorticoid, and is useful as a substitute for steroidal drugs.

  5'-Pseudouridyl N-oleoylcarbamate 由式（1）代表。该化合物具有显著增强皮质类固醇活性的生理活性，可作为类固醇药物的替代品。
• Hot-melt resin composition, its production in powder form and hot-melt resin powder composition
  申请人：SANYO CHEMICAL INDUSTRIES, LTD.

  公开号：EP0832953A2

  公开（公告）日：1998-04-01

  The present invention provides a hot-melt resin composition which comprises 1 to 30% by weight of a compound represented by the general formula (1)         Q-(X-A)n     (1) (wherein X is a urethane or urea group, Q is a group with a valence of n, A is a univalent group, one of Q and A being an isocyanate residue and the other being an amine or alcohol residue, and n is an integer of 1 to 3) and 70 to 99% by weight of a thermoplastic polyurethane resin (B); a method of producing a powder form of said hot-melt resin composition; and a hot-melt resin powder composition which comprises said powder-form hot-melt resin composition.

  本发明提供了一种热熔树脂组合物，该组合物包含 1 至 30%（按重量计）通式 (1) 所代表的化合物 Q-(X-A)n (1) (其中 X 是氨基甲酸酯或尿素基团，Q 是价数为 n 的基团，A 是单价基团，Q 和 A 中的一个是异氰酸酯残基，另一个是胺或醇残基，n 是 1 至 3 的整数）和重量百分比为 70 至 99% 的热塑性聚氨酯树脂 (B)；生产所述粉末状热熔树脂组合物的方法；以及包含所述粉末状热熔树脂组合物的热熔树脂粉末组合物。
• OIL-RESISTANT AGENT FOR PAPER
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP3851578A1

  公开（公告）日：2021-07-21

  The present invention provides an oil-resistant agent which is capable of imparting paper with excellent oil resistance and water resistance. The present invention discloses an oil-resistant agent for paper, which contains a non-fluorine copolymer that has a repeating unit formed from (a) an acrylic monomer having a long-chain hydrocarbon group with 7-40 carbon atoms and a repeating unit formed from (b) an acrylic monomer having a hydrophilic group. This oil-resistant agent for paper also contains a liquid medium that is composed of water and/or an organic solvent, preferably of water or a mixture (aqueous medium) of water and an organic solvent. It is preferable that the non-fluorine copolymer has a repeating unit formed from (c) a monomer having an ion donor group in addition to the repeating units formed from the monomers (a) and (b).

  本发明提供了一种耐油剂，它能够赋予纸张优异的耐油性和耐水性。本发明公开了一种纸张耐油剂，它含有一种无氟共聚物，该共聚物的重复单元由(a)具有 7-40 个碳原子的长链烃基的丙烯酸单体和(b)具有亲水基团的丙烯酸单体组成。这种纸张防油剂还含有一种液体介质，该介质由水和/或有机溶剂组成，最好是水或水与有机溶剂的混合物（水介质）。无氟共聚物除了由单体(a)和(b)形成的重复单元外，最好还具有由(c)单体形成的重复单元，该单体具有离子供体基团。