2-Hydroxymethylphthalimidin | 117491-65-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-Hydroxymethylphthalimidin
• 英文别名: 2-hydroxymethyl-2,3-dihydro-isoindol-1-one；2-(hydroxymethyl)-3H-isoindol-1-one
• CAS: 117491-65-3
• 化学式: C₉H₉NO₂
• 分子量: 163.176
• InChiKey: MFSPMZUEGYDSDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PORPHYRAZINE COLORING MATTER AND INK CONTAINING THE SAME
  申请人：Yoneda Takashi

  公开号：US20100126377A1

  公开（公告）日：2010-05-27

  The present invention relates to an ink composition containing a phthalocyanine coloring matter represented by the following formula (1): (wherein, each of the rings A to D independently represents a benzene ring or a pyridine ring, M represents a metal atom or the like, X represents a carbonyl group or the like, Y represents a hydrogen atom; a nitro group; a hydroxy group; a sulfo group; a carboxy group; an amino group; an alkoxy group, an alkylthio group, an alkylsulfonyl group which may be substituted; an aryloxy group, an arylthio group, an arylsulfonyl group, a heteroaryloxy group, a heteroarylthio group, a heteroarylsulfonyl group or an amino group, which may be substituted; or the like, and L is from 2 to 8) or a salt thereof; and said ink composition gives, in inkjet printing on plain paper, printed matters exhibiting an extremely excellent water fastness.
• [EN] 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF<br/>[FR] DERIVES 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE ET UTILISATION
  申请人：DAE WOONG PHARMA

  公开号：WO2002081446A1

  公开（公告）日：2002-10-17

  This invention relates to novel compounds of 3-cyclopentyloxy-4-methoxyphenyl-isoindolinone derivatives having the activity to inhibit tumor necrosis factor-α (TNF-α) or cyclic AMP phosphodiesterase IV (PDE 4). In more detail, this invention is directed to the preparation processes of the novel compounds of formula [1], and a pharmaceutically acceptable salt thereof, and pharmaceutical compositions possessing important biological therapeutic effect on inflammatory and autoimmune diseases associated with a detrimental excess of TNF-α.