4-chloromethyl-2-(2-hydroxynaphthylidenehydrazino)thiazole | 890306-64-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-chloromethyl-2-(2-hydroxynaphthylidenehydrazino)thiazole
• CAS: 890306-64-6
• 化学式: C₁₅H₁₂ClN₃OS
• 分子量: 317.799
• InChiKey: ISOULTYAGKJNNI-UHFFFAOYSA-N

物化性质

• 熔点：
  201 °C
• 沸点：
  539.0±60.0 °C(predicted)
• 密度：
  1.41±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.19
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  57.51
• 氢给体数：
  2.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  4-chloromethyl-2-(2-hydroxynaphthylidenehydrazino)thiazole 、 水 、 cobalt(II) acetate 在 NaOH 作用下， 以 乙醇 、 丙酮 为溶剂， 以70%的产率得到bis(4-chloromethyl-2-(2-hydroxynaphthylidenehydrazino)thiazole)cobalt(II) dihydrate
  参考文献：
  名称：

  Synthesis, Characterization, and Thermal Behavior of 4-Chloromethyl-2-(2-Hydroxynaphthylidenehydrazino) Thiazole and its Complexes with Cr(III), Co(II), Ni(II), and Cu(II)

  摘要：

  A new ligand, 4-chloromethyl-2-(2-hydroxynaphthylidenehydrazino) thiazole, has been synthesized from dichloroacetone and 2-hydroxynaphthylidenethiosemicarbazone. Metal complexes of the ligand were prepared from acetate salts of Co(II), Cu(II), Ni(II), and chloride of Cr(III) in dry acetone. Characterization of the ligand and its complexes were made by microanalyses, FT-IR, (13)C, (1)H NMR, and UV-Visible spectroscopy, magnetic susceptibility, thermogravimetric analysis. In the light of these results it was suggested that two ligands coordinate to each metal atom by hydroxyl oxygen, imino nitrogen and thiazole ring nitrogen to form high spin octahedral complexes with Cr(III), Co(II), Ni(II), and Cu(II).

  DOI：

  10.1080/15533170500359430