| 1352840-16-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• CAS: 1352840-16-4
• 化学式: C₃₀H₃₃Cl₃N₁₀O₃S₃
• 分子量: 784.214
• InChiKey: JKQZPEMBEAIDAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.86
• 重原子数：
  49.0
• 可旋转键数：
  15.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  173.19
• 氢给体数：
  9.0
• 氢受体数：
  10.0

反应信息

• 作为产物：
  描述：

  在 一水合肼 作用下， 以 乙醇 、 水 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  Synthesis and characterization of multimeric salicylaldimine thiosemicarbazones and their Pd(II) and Pt(II) complexes

  摘要：

  A series of di- and trithiosemicarbazone ligands as well as their Pd(II) and Pt(II) 1,3,5-triaza-7-phosphaadamantane (PTA) complexes have been synthesised using templated reactions between various substituted salicylaldimine thiosemicarbazone ligands and metal precursors of the general formula cis-[M(PTA)(2)Cl-2], where M = Pd or Pt. Characterization of these complexes was achieved using various analytical and spectroscopic techniques: elemental analysis, ESI-MS, FT-IR, and NMR (H-1, C-13{H-1) and P-31{H-1}) spectroscopy. The data revealed tridentate (O-N-S) coordination of the thiosemicarbazone moieties via the imine nitrogen, thiolato sulfur and phenolic oxygen to each metal center. in vitro biological evaluation of selected compounds was conducted against WHCO1 oesophageal cancer cells. Some of the multimeric compounds display some promising biological activity. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2011.10.005