9,12,15-triaza-3,6-dioxa-pentadecanol | 475977-33-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 9,12,15-triaza-3,6-dioxa-pentadecanol
• 英文别名: 2-[2-[2-[2-(2-aminoethylamino)ethylamino]ethoxy]ethoxy]ethanol
• CAS: 475977-33-4
• 化学式: C₁₀H₂₅N₃O₃
• 分子量: 235.327
• InChiKey: DCFWGOKPJFXSFD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  16
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  88.8
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  二乙烯三胺 、 (2-Iodoethoxy) ethoxyethanol 、 甲醇 在 二乙烯三胺 、 sodium hydroxide 、 二氯甲烷 、 Magnesium;disodium;carbonate;sulfate 作用下， 反应 1.0h， 以(5:1) to give 1.43 g (33%) of the title compound as a pale yellow oil的产率得到9,12,15-triaza-3,6-dioxa-pentadecanol
  参考文献：
  名称：

  Compositions for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences

  摘要：

  本发明的组成物包括一个或多个与无机或有机固体支撑物共价键结合的钯结合配体。这些与固体支撑物结合的钯结合配体可用于单一杂环胺基分离，或可用于从其他核苷酸或核苷酸链中分离包含特定序列的核苷酸链。在本发明的一个方面，每个存在的配体都单独与单个Pd（II）离子形成配合物。如果组成物中存在2到4个配体，则每个存在的配体必须至少与其他配体相隔3个原子，最好是从3到20个碳原子或等效间隔。

  公开号：

  US06774082B2

文献信息

• Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences
  申请人：IBC Advanced Technologies, Inc.

  公开号：US20030050458A1

  公开（公告）日：2003-03-13

  The compositions of the present invention comprise one or more palladium bound ligands that are covalently bonded to inorganic or organic solid supports. These palladium bound ligands bonded to solid supports can be used for single heterocyclic amine base separation, or can be used to separate nucleotide chain containing specific sequences from other nucleotides or nucleotide chains. In one aspect of the invention, each ligand present is individually complexed to a single Pd(II) ion. If there are from 2 to 4 ligands present in the composition, then each ligand present must be separated from the other ligands by at least 3 atoms, preferably from 3 to 20 carbon atoms or equivalent spacing.

  本发明的组合物包括一个或多个与无机或有机固体支撑物共价结合的钯配体。这些与固体支撑物结合的钯配体可用于单一杂环胺基分离，或者可用于将包含特定序列的核苷酸链与其他核苷酸或核苷酸链分离。在本发明的一个方面，每个存在的配体都与单个Pd(II)离子形成络合物。如果组合物中存在2到4个配体，则每个存在的配体必须与其他配体至少相隔3个原子，最好是在3到20个碳原子或等效间距之间。
• COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES
  申请人：IBC ADVANCED TECHNOLOGIES, INC.

  公开号：EP1453602A2

  公开（公告）日：2004-09-08
• EP1453602A4
  申请人：——

  公开号：EP1453602A4

  公开（公告）日：2005-01-12
• US6774082B2
  申请人：——

  公开号：US6774082B2

  公开（公告）日：2004-08-10
• [EN] COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES<br/>[FR] COMPOSITIONS ET METHODES DE SEPARATION DE BASES AMINEES AROMATIQUES HETEROCYCLIQUES, DE NUCLEOSIDES, DE NUCLEOTIDES ET DE SEQUENCES NUCLEOTIDIQUES
  申请人：IBC ADVANCED TECH INC

  公开号：WO2002092766A2

  公开（公告）日：2002-11-21

  The compositions of the present invention comprise one or more palladium bound ligands that are covalently bonded to inorganic or organic solid supports. These palladium bound ligands bonded to solid supports can be used for single heterocyclic amine base separation, or can be used to separate nucleotide chain containing specific sequences from other nucleotides or nucleotide chains. In one aspect of the invention, each ligand present is individually complexed to a single Pd(II)ion. If there are from 2 to 4 ligands present in the composition, then each ligand present must be separated from the other ligands by at least 3 atoms, preferably from 3 to 20 carbon atoms or equivalent spacing.