(S)-5,6-dihydroxy-hexanal (Ξ)-1->5-cyclohemiacetal | 18653-63-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: (S)-5,6-dihydroxy-hexanal (Ξ)-1->5-cyclohemiacetal
• 英文别名: (2Ξ,6S)-6-hydroxymethyl-tetrahydro-pyran-2-ol；(6S)-6-(hydroxymethyl)oxan-2-ol
• CAS: 18653-63-9
• 化学式: C₆H₁₂O₃
• 分子量: 132.159
• InChiKey: SIBRPBFHZUEONG-ZBHICJROSA-N

物化性质

• 沸点：
  266.1±25.0 °C(Predicted)
• 密度：
  1.168±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] SYNTHESIS OF ACETOXYACETALDEHYDE<br/>[FR] SYNTHÈSE D'ACÉTOXYACÉTALDÉHYDE
  申请人：LEK PHARMACEUTICALS

  公开号：WO2011064249A1

  公开（公告）日：2011-06-03

  The invention belongs to the field of organic chemistry and relates to a new synthesis of acetoxyacetaldehyde. Comprising the steps of providing monoacetyl ethylene glycol and converting it by oxidation using an N-oxyl compound in the presence of a co-oxidant.

  该发明属于有机化学领域，涉及一种新的乙醇酸乙酯醛的合成方法。包括以下步骤：提供单乙酰基乙二醇，并在存在共氧化剂的情况下，通过使用N-氧化剂化合物进行氧化转化。
• FILM FORMING DENTAL COMPOSITIONS
  申请人：3M Innovative Properties Company

  公开号：EP2178490B1

  公开（公告）日：2019-09-04
• NEAR-INFRARED DYE-CONJUGATED HYALURONIC ACID DERIVATIVE AND CONTRAST AGENT FOR OPTICAL IMAGING INCLUDING THEM
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20150374856A1

  公开（公告）日：2015-12-31

  Provided is a compound having a high ICG content that has high accumulation property in a tumor and has a large intensity of a photoacoustic signal emitted from the tumor even when a time period elapses after administration. Specifically, provided is a hyaluronic acid derivative to which polyethylene glycol and an ICG derivative are conjugated.