5-(4-benzhydrylpiperazin-1-yl)sulfonyl-N,N-dimethylnaphthalen-1-amine | 1443753-96-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-(4-benzhydrylpiperazin-1-yl)sulfonyl-N,N-dimethylnaphthalen-1-amine
• CAS: 1443753-96-5
• 化学式: C₂₉H₃₁N₃O₂S
• 分子量: 485.65
• InChiKey: LGSZYFFXJKMPRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  35
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  52.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  mercury(II) perchlorate 、 5-(4-benzhydrylpiperazin-1-yl)sulfonyl-N,N-dimethylnaphthalen-1-amine 以 aq. phosphate buffer 、 乙腈 为溶剂， 生成
  参考文献：
  名称：

  A simple blue fluorescent probe to detect Hg2+ in semiaqueous environment by intramolecular charge transfer mechanism

  摘要：

  An efficient intramolecular charge transfer fluorescent probe bridging benzhydryl moiety and dansyl fluorophore through piperazine unit has been synthesized and characterized. The photophysical behavior of synthesized probe has been analyzed in the presence of different cations in aqueous acetonitrile solution. The probe has shown sensitivity to detect Hg2+ selectively over other tested cations at 20 nM level. The probable mode of binding of Hg2+ through the nitrogen and oxygen atoms of piperazine and dansyl has been established by spectral data analysis. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.05.014
• 作为产物：
  描述：

  二苯甲醇 在 氯化亚砜 、 potassium carbonate 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 29.0h， 生成 5-(4-benzhydrylpiperazin-1-yl)sulfonyl-N,N-dimethylnaphthalen-1-amine
  参考文献：
  名称：

  A simple blue fluorescent probe to detect Hg2+ in semiaqueous environment by intramolecular charge transfer mechanism

  摘要：

  An efficient intramolecular charge transfer fluorescent probe bridging benzhydryl moiety and dansyl fluorophore through piperazine unit has been synthesized and characterized. The photophysical behavior of synthesized probe has been analyzed in the presence of different cations in aqueous acetonitrile solution. The probe has shown sensitivity to detect Hg2+ selectively over other tested cations at 20 nM level. The probable mode of binding of Hg2+ through the nitrogen and oxygen atoms of piperazine and dansyl has been established by spectral data analysis. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.05.014