p-Hydroxyphenyldimethylphosphonat | 15286-25-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: p-Hydroxyphenyldimethylphosphonat
• 英文别名: 4-Dimethoxyphosphorylphenol
• CAS: 15286-25-6
• 化学式: C₈H₁₁O₄P
• 分子量: 202.147
• InChiKey: YCYLCVMIVJNHOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-溴苯酚 、 三甲氧基磷 以 1,4-二氧六环 为溶剂， 以77%的产率得到p-Hydroxyphenyldimethylphosphonat
  参考文献：
  名称：

  通过紫外线诱导的光 Arbuzov 反应形成环芳基和芳基卤化物的 C-P 键：膦酸盐接枝支架的多功能入口

  摘要：

  一种新的通用方法，用于通过紫外诱导的光 Arbuzov 反应与亚磷酸三甲酯形成（杂）芳基卤化物的 C-P 键，在温和的反应条件下获得不同的膦酸酯接枝芳烃、杂芳烃和共面堆叠的环芳烃，而无需开发了对催化剂、添加剂或碱的需求。UV 诱导的光 Arbuzov 协议具有广泛的合成范围，具有大的官能团兼容性，例如 30 多种衍生物。除了单膦酸盐外，二膦酸盐和三膦酸盐的收率也很高。温和和不含过渡金属的反应条件巩固了该方法合成药物相关化合物和超分子纳米结构材料前体的潜力。

  DOI：

  10.1039/d2ra00094f

文献信息

• [EN] 1 H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1 H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)<br/>[FR] DÉRIVÉS DE 1H-PYRAZOLO [4,3-G] ISOQUINOLÉINE ET DE 1H-PYRAZOLO [4,3-G] QUINOLÉINE EN TANT QUE MODULATEURS D'ALPHA-1-ANTITRYPSINE POUR TRAITER UNE DÉFICIENCE EN ALPHA-1-ANTITRYPSINE (AATD)
  申请人：VERTEX PHARMA

  公开号：WO2021203025A1

  公开（公告）日：2021-10-07

  1H-pyrazolo[4,3-g]isoquinoline and 1H-pyrazolo[4,3-g]quinoline derivatives as alpha-1-antitrypsin modulators for treating alpha-1- antitrypsin deficiency (AATD).

  1H-吡唑并[4,3-g]异喹啉和1H-吡唑并[4,3-g]喹啉衍生物作为α-1-抗胰蛋白酶调节剂，用于治疗α-1-抗胰蛋白酶缺乏症（AATD）。
• Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product
  申请人：Kageyama Katsuhiko

  公开号：US20080249280A1

  公开（公告）日：2008-10-09

  This invention provides a polyester and a polyester molded product, which, while maintaining color tone, transparency, and thermal stability, can realize a high polycondensation rate, are less likely to cause the production of polycondensation catalyst-derived undesired materials, and can simultaneously meet both quality and cost effectiveness requirements, which can exhibit the characteristic features, for example, in the fields of ultrafine fibers, high transparent films for optical use, or ultrahigh transparent molded products. These advantages can be realized by using, in the production of a polyester in the presence of an aluminum compound-containing polyester polycondensation catalyst, an aluminum compound having an absorbance of not more than 0.0132 as measured in the form of an aqueous aluminum compound solution, prepared by dissolving the aluminum compound in pure water to give a concentration of 2.7 g/liter in terms of the amount of aluminum element, under conditions of cell length 1 cm and wavelength 680 nm.

  本发明提供了一种聚酯和聚酯成型产品，可以在保持色调、透明度和热稳定性的同时，实现高聚酯化速率，不太可能引起聚酯化催化剂来源的不良材料的生产，并且可以同时满足质量和成本效益的要求，这些优点可以在超细纤维、用于光学的高透明薄膜或超高透明成型产品等领域展现出特征性能。通过在含有铝化合物聚酯聚合催化剂的聚酯生产中使用具有吸光度不超过0.0132的铝化合物，可以实现这些优点。该吸光度是在细胞长度为1厘米，波长为680纳米的条件下，将铝化合物溶解在纯水中以给定铝元素量浓度为2.7克/升形成的水溶性铝化合物溶液中测量得出的。
• POLYESTER POLYMERIZATION CATALYST, POLYESTER PRODUCED THEREWITH AND PROCESS FOR PRODUCING THE POLYESTER
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1719790A1

  公开（公告）日：2006-11-08

  The invention provides a polyester produced in the presence of a polycondensation catalyst comprising at least one compound selected from a group consisting of aluminum compounds and at least one compound selected from a group consisting of phosphorus compounds and being excellent in color tone, thermal stability, and transparency and improved in terms of insoluble particles. Particularly, the invention provides a polyester in which the content of an aluminum containing insoluble particles in the polyester is 3500 ppm or lower and a polyester which has a haze value of 2% or lower when being formed into a monoaxially oriented film. The aluminum catalyst for attaining these characteristics and properties may be polyester polymerization catalyst obtained by mixing an aluminum compound and a phosphorus compound in a solvent and has specified spectral characteristics in the side measurement of 31P-NMR spectrum and 27Al-NMR spectrum.

  本发明提供了一种在缩聚催化剂存在下生产的聚酯，该催化剂由至少一种选自铝化合物和至少一种选自磷化合物的化合物组成，具有优异的色调、热稳定性和透明度，并在不溶性颗粒方面有所改进。特别是，本发明提供了一种聚酯，其中聚酯中含铝不溶性颗粒的含量为 3500 ppm 或更低，以及一种聚酯，在形成单轴拉伸薄膜时，雾度值为 2% 或更低。用于获得这些特征和特性的铝催化剂可以是通过在溶剂中混合铝化合物和磷化合物而获得的聚酯聚合催化剂，并且在 31P-NMR 光谱和 27Al-NMR 光谱的侧面测量中具有特定的光谱特性。
• POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1932867A1

  公开（公告）日：2008-06-18

  Disclosed is a polyester produced from an aluminum compound and a phosphorus compound in the presence of a polycondensation catalyst. The polyester contains a polyester-insoluble, aluminum-containing insoluble particle in an amount of 1000 ppm or less as quantified by the method disclosed in the description, and contains an acid terminal group at a ratio of 10 to 50 eq/ton. The polyester can provide a highly transparent molded article produced through drawing (e.g., a film or hollow molded article) and is useful in the fields of highly transparent optical films, ultra-highly transparent molded articles or the like.

  本发明公开了一种在缩聚催化剂存在下由铝化合物和磷化合物制得的聚酯。该聚酯含有聚酯不溶物、含铝不溶物颗粒，按描述中公开的方法定量，其含量为 1000 ppm 或更少，并含有酸性末端基团，其比例为 10 至 50 eq/吨。该聚酯可提供通过拉丝生产的高透明模塑品（如薄膜或中空模塑品），在高透明光学薄膜、超高透明模塑品等领域非常有用。
• POLYESTER FILM FOR PROTECTION OF BACK SURFACES OF SOLAR CELLS
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP2484714A1

  公开（公告）日：2012-08-08

  It is an object of the present invention to provide a polyester film for the protection of a back surface of a solar cell which, when applied to a silicon thin film solar cell, exhibits excellent durability even under high-temperature and high-humidity conditions and long term thermal stability. A polyester film for the protection of a back surface of a solar cell containing a polyester, as a main constituent, obtained by polymerization using a polycondensation catalyst containing aluminum and/or its compound as well as a phosphorus compound having an aromatic group in the molecule; having a whiteness degree of 50 or higher; containing 3 to 50% by mass of fine particles with a mean particle diameter of 0.1 to 3 µm; and having an acid value from not lower than 1 (eq/ton) and not higher than 30 (eq/ton).

  本发明的目的是提供一种用于保护太阳能电池背面的聚酯薄膜，这种薄膜在应用于硅薄膜太阳能电池时，即使在高温高湿条件下也能表现出极佳的耐久性和长期热稳定性。 一种用于保护太阳能电池背面的聚酯薄膜，其主要成分为聚酯，该聚酯通过使用含铝和/或其化合物以及分子中含有芳香基的磷化合物的缩聚催化剂聚合而成；白度为 50 或更高；含有 3 至 50%（按重量计）的细颗粒，其平均颗粒直径为 0.1 至 3 微米；酸值不低于 1（当量/吨），不高于 30（当量/吨）。