| 1629626-83-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• CAS: 1629626-83-0
• 化学式: C₃₄H₂₆N₂O₃*ClH
• 分子量: 547.053
• InChiKey: XECHBUGRKMEHGE-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  tetramethyl rhodamine chloride 在 甲基丙烯酸羟乙酯 、 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Synthesis, chemical reactivity, and photophysical properties of 2′,7′ phenylated rhodamine dyes

  摘要：

  While exploring water soluble rhodamine based fluorescent polymeric systems for biological imaging applications we came across new rhodamine derivatives that possess interesting optical properties. We report the synthesis of three different 2 ',7 '-diphenylated rhodamine derivatives (1-3) with distinct photophysical properties. The three rhodamine derivatives differ by the number of methyl groups present on the nitrogens and their absorption maxima are red-shifted on increased methylation. We observed an unusual inertness of these compounds toward traditional DCC-DMAP esterification conditions, which we attribute to the ease of lactonization in the presence of even minute amounts of the nucleophile/base DMAP (pK(a) = 9.2). Synthesis of acrylate esters was successfully accomplished using MSNT (1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole) coupling conditions using a much milder nucleophile/base, for example, N-methyl imidazole (pK(a) = 6.95). (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.124