6,22-bis[bis(dimethylamino)phosphanyloxy]-N,N-dimethyl-13,15-dioxa-14-phosphapentacyclo[14.8.0.03,12.04,9.019,24]tetracosa-1(16),3(12),4(9),5,7,10,17,19(24),20,22-decaen-14-amine | 861988-07-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6,22-bis[bis(dimethylamino)phosphanyloxy]-N,N-dimethyl-13,15-dioxa-14-phosphapentacyclo[14.8.0.03,12.04,9.019,24]tetracosa-1(16),3(12),4(9),5,7,10,17,19(24),20,22-decaen-14-amine
• CAS: 861988-07-0
• 化学式: C₃₁H₄₂N₅O₄P₃
• 分子量: 641.627
• InChiKey: UFTCTAOUOWBNPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  43
• 可旋转键数：
  9
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  53.1
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  6,22-bis[bis(dimethylamino)phosphanyloxy]-N,N-dimethyl-13,15-dioxa-14-phosphapentacyclo[14.8.0.03,12.04,9.019,24]tetracosa-1(16),3(12),4(9),5,7,10,17,19(24),20,22-decaen-14-amine 在 resorcin-(4-Me)-(6-C₁₀H₂₁) 作用下， 以 1,4-二氧六环 为溶剂， 生成 3-N,3-N,13-N,13-N,23-N,23-N,33-N,33-N-octamethyl-2,4,12,14,22,24,32,34-octaoxa-3,13,23,33-tetraphosphaundecacyclo[23.15.7.75,21.028,46.031,45.035,43.038,42.08,53.011,52.015,50.018,49]tetrapentaconta-1(41),5(54),6,8(53),9,11(52),15(50),16,18(49),19,21(48),25(47),26,28(46),29,31(45),35(43),36,38(42),39-icosaene-3,13,23,33-tetramine
  参考文献：
  名称：

  Synthesis of phosphocyclic 2,2′,7,7′-tetrahydroxydinaphthylmethane derivatives

  摘要：

  Two types of phosphocyclic derivatives were synthesized by phosphorylation of 2,2',7,7'-tetrahydroxydinaphthylmethane with triamidophosphites: triphosphorus containing compounds with a phosphocine ring and two acyclic diamidophosphite fragments, and tetraphosphorus-containing macrocycles with a 24-membered ring and two eight-membered phosphorus rings. It was shown that interaction of triphosphorus compounds with resorcinarene gives tetraphosphorus macrocycles. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.05.051
• 作为产物：
  描述：

  2,7-二羟基萘 在 sodium carbonate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 48.5h， 生成 6,22-bis[bis(dimethylamino)phosphanyloxy]-N,N-dimethyl-13,15-dioxa-14-phosphapentacyclo[14.8.0.03,12.04,9.019,24]tetracosa-1(16),3(12),4(9),5,7,10,17,19(24),20,22-decaen-14-amine
  参考文献：
  名称：

  A new family of macrocyclic phosphorus compounds

  摘要：

  DOI：

  10.1134/s0012500807050084

文献信息

• Regiodirected phosphorylation of 2,2′,7,7′-tetrahydroxydinaphthylmethane
  作者：Vera I. Maslennikova、Tatyana Yu. Sotova、Larisa K. Vasyanina、Konstantin A. Lyssenko、Mikhail Yu. Antipin、Sergei O. Adamson、Andrei I. Dementyev、Wolf D. Habicher、Eduard E. Nifantyev

  DOI：10.1016/j.tet.2007.02.095

  日期：2007.5

  studied and the influence of molecule pre-organization on the regioselectivity of functionalization was investigated. The reactions of 2,2′,7,7′-tetrahydroxydinaphthylmethane with phosphorous amides containing 1–3 amide bonds gave oligophosphorylated derivatives differing in the number and the nature of phosphorus fragments and in the size of phosphorus rings: tetraphosphorus macrocycles containing one

  研究了2,2'，7,7'-四羟基二萘甲基甲烷的磷酸化，并研究了分子预组织对官能化区域选择性的影响。2,2'，7,7'-四羟基二萘甲甲烷与含有1-3个酰胺键的磷酰胺的反应生成的寡磷酸化衍生物的磷片段的数量和性质以及磷环的大小不同：四磷大环含有一个24-元和两个八元磷环，包含磷环和两个无环磷片段的三磷化合物以及分子中具有四个磷基的四磷酸化衍生物。证明了通过使用PN键数量和活性不同的试剂来控制磷酸化区域选择性的可能性。