1-pentoxy-4-[(E)-2-[4-[4-[(E)-2-(4-pentoxyphenyl)ethenyl]phenyl]phenyl]ethenyl]benzene | 1416403-58-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1-pentoxy-4-[(E)-2-[4-[4-[(E)-2-(4-pentoxyphenyl)ethenyl]phenyl]phenyl]ethenyl]benzene
• CAS: 1416403-58-1
• 化学式: C₃₈H₄₂O₂
• 分子量: 530.75
• InChiKey: BDXKTNFWAYXNQM-WGDLNXRISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.6
• 重原子数：
  40
• 可旋转键数：
  15
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-溴戊烷 、 4,4'-二溴联苯 、 甲基三苯基碘化膦 、 对羟基苯甲醛 在 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) 、 四丁基溴化铵 、 palladium diacetate 、 potassium carbonate 作用下， 以 N,N-二甲基乙酰胺 为溶剂， 反应 40.0h， 以31%的产率得到1-pentoxy-4-[(E)-2-[4-[4-[(E)-2-(4-pentoxyphenyl)ethenyl]phenyl]phenyl]ethenyl]benzene
  参考文献：
  名称：

  Synthesis of alkyloxy stilbenes by one-pot O-alkylation-Wittig and O-alkylation-Wittig–Heck reaction sequence

  摘要：

  A new route for the synthesis of allcyloxy stilbenes from hydroxy benzaldehydes is developed by a combination of one-pot reactions. Tandem one-pot O-alkylation-Wittig and O-alkylation-Wittig-Heck reactions offer a simple access to conjugated alkyloxy stilbenes. A highly conjugated tetra(p-alkyloxystyryl) benzene was synthesized from 1,2,4,5-tetrabromobenzene involving a series of one-pot operations following the O-alkylation-Wittig-Heck scheme. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.10.102

文献信息

• Synthesis of alkyloxy stilbenes by one-pot O-alkylation-Wittig and O-alkylation-Wittig–Heck reaction sequence
  作者：Krupa N. Patel、Bola V. Kamath、Ashutosh V. Bedekar

  DOI：10.1016/j.tetlet.2012.10.102

  日期：2013.1

  A new route for the synthesis of allcyloxy stilbenes from hydroxy benzaldehydes is developed by a combination of one-pot reactions. Tandem one-pot O-alkylation-Wittig and O-alkylation-Wittig-Heck reactions offer a simple access to conjugated alkyloxy stilbenes. A highly conjugated tetra(p-alkyloxystyryl) benzene was synthesized from 1,2,4,5-tetrabromobenzene involving a series of one-pot operations following the O-alkylation-Wittig-Heck scheme. (C) 2012 Elsevier Ltd. All rights reserved.