N-(4-hydroxyimino-2-methyl-2-pentyl)-N-isopropylhydroxylamine | 65483-70-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(4-hydroxyimino-2-methyl-2-pentyl)-N-isopropylhydroxylamine
• 英文别名: N-(4-hydroxyimino-2-methylpentan-2-yl)-N-propan-2-ylhydroxylamine
• CAS: 65483-70-7
• 化学式: C₉H₂₀N₂O₂
• 分子量: 188.27
• InChiKey: NDAUWJAJKVCZQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  56.1
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-(4-hydroxyimino-2-methyl-2-pentyl)-N-isopropylhydroxylamine 在 氧气 作用下， 生成 2,2,4,6,6-pentamethyl-1,2,5,6-tetrahydropyridine-3-oxide-1-oxyl
  参考文献：
  名称：

  Synthesis of acetonine nitroxide radical and 1-hydroxy-2,2,4,6,6-pentamethyl-1,2,5,6-tetrahydropyrimidine

  摘要：

  An oxidation of acetonine with hydrogen peroxide 30% in strong basic water media in the presence of sodium tungstate with subsequent reduction of reaction product with hydrazine hydrate afforded up to 50% yields of the title hydroxyderivative. Mild oxidation of this compound with MnO2 in ether gave acetonine nitroxide radical quantitatively. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)02049-3
• 作为产物：
  描述：

  甲基碘化镁 、 N-(4-Hydroxyimino-2-methyl-2-pentyl)hydroxylamin 、 乙醛 生成 N-(4-hydroxyimino-2-methyl-2-pentyl)-N-isopropylhydroxylamine
  参考文献：
  名称：

  Synthesis of acetonine nitroxide radical and 1-hydroxy-2,2,4,6,6-pentamethyl-1,2,5,6-tetrahydropyrimidine

  摘要：

  An oxidation of acetonine with hydrogen peroxide 30% in strong basic water media in the presence of sodium tungstate with subsequent reduction of reaction product with hydrazine hydrate afforded up to 50% yields of the title hydroxyderivative. Mild oxidation of this compound with MnO2 in ether gave acetonine nitroxide radical quantitatively. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)02049-3