3-[2-[[3-[2-[bis[3-[2-[bis[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]ethylimino]-3-hydroxypropyl]amino]ethyl-[3-[2-[bis[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]ethylimino]-3-hydroxypropyl]amino]-1-hydroxypropylidene]amino]ethyl-[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]-N-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethyl]propanimidic acid | 1498305-18-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 3-[2-[[3-[2-[bis[3-[2-[bis[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]ethylimino]-3-hydroxypropyl]amino]ethyl-[3-[2-[bis[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]ethylimino]-3-hydroxypropyl]amino]-1-hydroxypropylidene]amino]ethyl-[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]-N-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethyl]propanimidic acid
• CAS: 1498305-18-2
• 化学式: C₁₈₂H₂₁₆N₃₄O₂₈
• 分子量: 3327.93
• InChiKey: ITGZLZSRSVJKQM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  18.2
• 重原子数：
  244
• 可旋转键数：
  99
• 环数：
  24.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  806
• 氢给体数：
  20
• 氢受体数：
  54

反应信息

• 作为产物：
  描述：

  正丙胺 、 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以92%的产率得到3-[2-[[3-[2-[bis[3-[2-[bis[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]ethylimino]-3-hydroxypropyl]amino]ethyl-[3-[2-[bis[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]ethylimino]-3-hydroxypropyl]amino]-1-hydroxypropylidene]amino]ethyl-[3-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethylimino]-3-hydroxypropyl]amino]-N-[2-[1,3-dioxo-6-(propylamino)benzo[de]isoquinolin-2-yl]ethyl]propanimidic acid
  参考文献：
  名称：

  Synthesis and functional characteristics of two new yellow-green fluorescent PAMAM dendrimers periphery modified with 1,8-naphthalimides

  摘要：

  The synthesis of two new poly(amidoamine) dendrimers from first generation modified with 1,8-naphthalimide fluorescent units is described. Their photophysical characteristics have been investigated in organic solvents of different polarity in order to investigate their sensor potential. Selectivity for detection of cuprum cations has been demonstrated. (C) 2013 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2013.09.023

文献信息

• Synthesis and functional characteristics of two new yellow-green fluorescent PAMAM dendrimers periphery modified with 1,8-naphthalimides
  作者：Stanislava Yordanova、Ivo Grabchev、Stanimir Stoyanov、Vanina Milusheva、Ivan Petkov

  DOI：10.1016/j.ica.2013.09.023

  日期：2014.1

  The synthesis of two new poly(amidoamine) dendrimers from first generation modified with 1,8-naphthalimide fluorescent units is described. Their photophysical characteristics have been investigated in organic solvents of different polarity in order to investigate their sensor potential. Selectivity for detection of cuprum cations has been demonstrated. (C) 2013 Elsevier B. V. All rights reserved.