2-[(Z)-2-(benzenesulfonyl)-1,2-dichloroethenyl]naphthalene | 1551100-29-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-[(Z)-2-(benzenesulfonyl)-1,2-dichloroethenyl]naphthalene
• CAS: 1551100-29-8
• 化学式: C₁₈H₁₂Cl₂O₂S
• 分子量: 363.264
• InChiKey: YWXZUMNYERIOHT-ISLYRVAYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯磺酰氯 、 2-(chloroethynyl)naphthalene 在 三对苯甲基膦 、 iron(II) chloride 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 36.0h， 以80%的产率得到
  参考文献：
  名称：

  Synthesis of cis-1,2-dichlorovinylsulfones via Fe-catalyzed regio- and stereoselective addition of sulfonyl chlorides to aromatic chloroalkynes

  摘要：

  An iron-catalyzed regio- and stereoselective chlorosulfonylation of aryl chloroalkynes has been described, producing cis-1,2-dichlorovinylsulfones in satisfactory yields with good to excellent stereoselectivity (Z/E up to 95:5). A variety of functional groups such as F, NO2, Cl, Br, OMe, and t-Bu are found to be compatible under the reaction conditions. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.12.063

文献信息

• Synthesis of cis-1,2-dichlorovinylsulfones via Fe-catalyzed regio- and stereoselective addition of sulfonyl chlorides to aromatic chloroalkynes
  作者：Lina Wang、Hui Zhu、Jianwei Che、Yuanfa Yang、Gangguo Zhu

  DOI：10.1016/j.tetlet.2013.12.063

  日期：2014.1

  An iron-catalyzed regio- and stereoselective chlorosulfonylation of aryl chloroalkynes has been described, producing cis-1,2-dichlorovinylsulfones in satisfactory yields with good to excellent stereoselectivity (Z/E up to 95:5). A variety of functional groups such as F, NO2, Cl, Br, OMe, and t-Bu are found to be compatible under the reaction conditions. (C) 2013 Elsevier Ltd. All rights reserved.