[2-(bithien-2'-yl)benzoxazol-5-yl]-L-alanine | 1058176-60-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 双噻吩和低聚噻吩
• 英文名称: [2-(bithien-2'-yl)benzoxazol-5-yl]-L-alanine
• 英文别名: (2S)-2-amino-3-[2-(5-thiophen-2-ylthiophen-2-yl)-1,3-benzoxazol-5-yl]propanoic acid
• CAS: 1058176-60-5
• 化学式: C₁₈H₁₄N₂O₃S₂
• 分子量: 370.453
• InChiKey: DPIFKPYVEQKMGO-NSHDSACASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  146
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  N-tert-butyloxycarbonyl [2-(bithien-2'-yl)benzoxazol-5-yl]-L-alanine 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以55%的产率得到[2-(bithien-2'-yl)benzoxazol-5-yl]-L-alanine
  参考文献：
  名称：

  Heteroaromatic alanine derivatives bearing (oligo)thiophene units: synthesis and photophysical properties

  摘要：

  A series of new benzoxazolylalanine derivatives bearing (oligo)thiophene units at the side chain were synthesized in good yields. The photophysical characterization of these amino acids was performed by UV-vis absorption and fluorescence emission studies and revealed that some of the compounds display high fluorescent quantum yields, making them good candidates for application as fluorescent probes. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.109

文献信息

• Heteroaromatic alanine derivatives bearing (oligo)thiophene units: synthesis and photophysical properties
  作者：Susana P.G. Costa、Elisabete Oliveira、Carlos Lodeiro、M. Manuela M. Raposo

  DOI：10.1016/j.tetlet.2008.06.109

  日期：2008.9

  A series of new benzoxazolylalanine derivatives bearing (oligo)thiophene units at the side chain were synthesized in good yields. The photophysical characterization of these amino acids was performed by UV-vis absorption and fluorescence emission studies and revealed that some of the compounds display high fluorescent quantum yields, making them good candidates for application as fluorescent probes. (C) 2008 Elsevier Ltd. All rights reserved.