| 906648-68-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• CAS: 906648-68-8
• 化学式: C₁₈H₁₆N₂
• 分子量: 260.338
• InChiKey: BQMMQMVAOVEURE-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  三甲基氰硅烷 、 在 tris(2,2'-bipyridyl)ruthenium dichloride 、 氧气 作用下， 以 乙腈 为溶剂， 反应 14.0h， 以80%的产率得到
  参考文献：
  名称：

  Visible-light-induced cyanation of aza-Baylis–Hillman adducts: a Michael type addition

  摘要：

  Visible-light-induced aerobic oxidative cyanation of aza-Baylis-Hillman (aza-BH) adducts providing valuable allylic cyanides in good to excellent yields has been developed. The protocol involves in situ formation of 4 pi conjugated iminium ion intermediates, which undergo cyanation at the gamma-position to afford Michael type adducts. This is the first example of visible-light-induced catalytic functionalization of aza-BH adducts using air (O-2) as an economical and ecosustainable oxidant and TMSCN as a convenient and readily available cyanide source. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.01.121