7-Benzyl-1-nitronaphthalen-2-ol | 1364525-23-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 7-Benzyl-1-nitronaphthalen-2-ol
• 英文别名: 7-benzyl-1-nitronaphthalen-2-ol
• CAS: 1364525-23-4
• 化学式: C₁₇H₁₃NO₃
• 分子量: 279.295
• InChiKey: JMIJXCKOPQTMRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  66
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  7-benzylnaphthalen-2-ol 在 2,3,5,6-四溴-4-甲基-4-硝基-2,5-环己二烯-1-酮 作用下， 以 乙醚 为溶剂， 生成 7-Benzyl-1-nitronaphthalen-2-ol
  参考文献：
  名称：

  Facile synthesis of 2,3,5,6-tetrabromo-4-methyl-nitrocyclohexa-2,5-dien-1-one, a mild nitration reagent

  摘要：

  Nitrocylcohexadienones have been applied as nitration reagents for mild, mono-nitrating reactions. The original synthesis of 2,3,5,6-tetrabromo-4-methyl-4-nitrocylcohexa-2,5-dien-1-one appeared to be difficult to pursue due to both the solvent system and reaction conditions. Therefore, we applied a modified solvent system and optimized the reaction conditions to prepare the dienone at 0 degrees C, to eventually overcome the difficulties. Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2012.01.066

文献信息

• Facile synthesis of 2,3,5,6-tetrabromo-4-methyl-nitrocyclohexa-2,5-dien-1-one, a mild nitration reagent
  作者：Christopher K. Arnatt、Yan Zhang

  DOI：10.1016/j.tetlet.2012.01.066

  日期：2012.3

  Nitrocylcohexadienones have been applied as nitration reagents for mild, mono-nitrating reactions. The original synthesis of 2,3,5,6-tetrabromo-4-methyl-4-nitrocylcohexa-2,5-dien-1-one appeared to be difficult to pursue due to both the solvent system and reaction conditions. Therefore, we applied a modified solvent system and optimized the reaction conditions to prepare the dienone at 0 degrees C, to eventually overcome the difficulties. Published by Elsevier Ltd.