Biphenyl-3-yl-[(9H-fluoren-9-ylmethoxycarbonylamino)]-acetic acid | 2351924-32-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: Biphenyl-3-yl-[(9H-fluoren-9-ylmethoxycarbonylamino)]-acetic acid
• 英文别名: [1,1'-Biphenyl]-3-acetic acid, alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-；2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-(3-phenylphenyl)acetic acid
• CAS: 2351924-32-6
• 化学式: C₂₉H₂₃NO₄
• 分子量: 449.506
• InChiKey: PWRYJYDNUXZTTJ-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  Biphenyl-3-yl-[(9H-fluoren-9-ylmethoxycarbonylamino)]-acetic acid 、 3-amidino-benzoic acid TFA salt 、 alkaline earth salt of/the/ methylsulfuric acid 生成 N-{[(4-Aminomethyl-cyclohexylmethyl)-carbamoyl]-biphenyl-3-yl-methyl}-3-carbamimidoyl-benzamide
  参考文献：
  名称：

  The design of phenylglycine containing benzamidine carboxamides as potent and selective inhibitors of factor Xa

  摘要：

  Factor Xa, a critical serine protease in the blood coagulation cascade, has become a target for inhibition as a strategy for the invention of novel anti-thrombotic agents. Here we describe the development of phenylglycine containing benzamidine carboxamides as novel, potent and selective inhibitors of factor Xa. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(01)00042-7