Ethynyl-phosphonic acid but-3-enyl ester pent-4-enyl ester | 392234-21-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: Ethynyl-phosphonic acid but-3-enyl ester pent-4-enyl ester
• 英文别名: 5-(But-3-enoxy-ethynyl-oxidophosphaniumyl)oxypent-1-ene；5-(but-3-enoxy-ethynyl-oxidophosphaniumyl)oxypent-1-ene
• CAS: 392234-21-8
• 化学式: C₁₁H₁₇O₃P
• 分子量: 228.228
• InChiKey: ZYCDMGUAYMOALI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  41.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Ethynyl-phosphonic acid but-3-enyl ester pent-4-enyl ester 在 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以83%的产率得到3,4,8,9-tetrahydro-2H-1,10-dioxa-10a-phospha-heptalene 10a-oxide
  参考文献：
  名称：

  Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis

  摘要：

  A versatile route of synthesis of phosphorus oxide and phosphorus borane templates starting from the bifunctional phosphorylating agent bis(diisopropylamino)ethynyiphosphine is presented. Ring-closing enyne metathesis using 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene complex 3 on these types of substrates led to the formation of mono- and bicyclic phosphorus heterocycles. (C) 2001 Elsvier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01740-3
• 作为产物：
  描述：

  在 四氮唑 、 叔丁基过氧化氢 作用下， 以 乙腈 为溶剂， 反应 0.08h， 生成 Ethynyl-phosphonic acid but-3-enyl ester pent-4-enyl ester
  参考文献：
  名称：

  Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis

  摘要：

  A versatile route of synthesis of phosphorus oxide and phosphorus borane templates starting from the bifunctional phosphorylating agent bis(diisopropylamino)ethynyiphosphine is presented. Ring-closing enyne metathesis using 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene complex 3 on these types of substrates led to the formation of mono- and bicyclic phosphorus heterocycles. (C) 2001 Elsvier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01740-3

文献信息

• Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis
  作者：Mattie S.M Timmer、Huib Ovaa、Dmitri V Filippov、Gijs A van der Marel、Jacques H van Boom

  DOI：10.1016/s0040-4039(01)01740-3

  日期：2001.11

  A versatile route of synthesis of phosphorus oxide and phosphorus borane templates starting from the bifunctional phosphorylating agent bis(diisopropylamino)ethynyiphosphine is presented. Ring-closing enyne metathesis using 4,5-dihydro-imidazol-2-ylidene ruthenium benzylidene complex 3 on these types of substrates led to the formation of mono- and bicyclic phosphorus heterocycles. (C) 2001 Elsvier Science Ltd. All rights reserved.