thioxobis(1-methylhydrazino)phosphoranyl azide | 156457-68-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: thioxobis(1-methylhydrazino)phosphoranyl azide
• 英文别名: bis(1-methylhydrazino)thiophosphonyl azide；N3PS(NCH3NH2)2；1-[[Amino(methyl)amino]-azidophosphinothioyl]-1-methylhydrazine
• CAS: 156457-68-0
• 化学式: C₂H₁₀N₇PS
• 分子量: 195.188
• InChiKey: CRUXFBXTWBFFNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  thioxobis(1-methylhydrazino)phosphoranyl azide 、 [(E)-2-(4-Diphenylphosphanyl-phenyl)-vinyl]-phosphonic acid diethyl ester 以 二氯甲烷 为溶剂， 反应 72.0h， 以100%的产率得到
  参考文献：
  名称：

  磷基树突的合成及核和表面反应性

  摘要：

  从独特的前体 (EtO)2P(O)CH=CHC6H4PPh2 (3-G0) 开始合成了一系列含磷树枝，其 X 射线晶体结构显示两种磷之间的扩展平面性。与膦基上官能化叠氮化物的施陶丁格反应是树突生长的第一步，使用发散方法继续进行。几种类型的反应在多种尺寸的树枝上进行，无论是在核心水平还是在表面水平。在核心水平将三氟甲磺酸甲酯特别添加到 P=S 和三甲基甲硅烷基三氟甲磺酸酯到 P=O，提供了双阳离子物质。13C NMR 光谱研究表明电荷离域的程度。磷烷接枝在第二代树突的表面，用于络合 PdCl2。这两种化合物都具有五种不同类型的磷原子，这有助于通过 31P NMR 光谱对其进行表征。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

  DOI：

  10.1002/ejic.200400016
• 作为产物：
  描述：

  bis(1-methylhydrazino)thiophosphonyl chloride 在 二苯并-18-冠醚-6 、 sodium azide 作用下， 以 四氢呋喃 为溶剂， 反应 96.0h， 以60%的产率得到thioxobis(1-methylhydrazino)phosphoranyl azide
  参考文献：
  名称：

  Synthesis of Di- or Tetrafunctionalized Phosphorus Macrocycles

  摘要：

  功能化磷酸二酰肼 RP(X)[NMeNH2]2 (R=Cl, N3) (1) 与有机 (2) 或磷 (4) 二醛反应，合成二或四功能化磷大环化合物 3a-d, 5a -h 产量良好。用叠氮化钠将含有大环的PCl定量转化为含有大环的PN3。所有化合物都是穴状配体和多大环物质的有用前体。

  DOI：

  10.1055/s-1995-4020

文献信息

• Synthesis of Onion-Peel Nanodendritic Structures with Sequential Functional Phosphorus Diversity
  作者：Nadia Katir、Nabil El Brahmi、Abdelkrim El Kadib、Serge Mignani、Anne-Marie Caminade、Mosto Bousmina、Jean Pierre Majoral

  DOI：10.1002/chem.201500138

  日期：2015.4.20

  of novel families of phosphorus‐based macromolecular architectures called “onion peel” phosphorus nanodendritic systems is reported. This construct is based on the versatility of methods of synthesis using several building blocks and on the capability of these systems to undergo regioselective reactions within the cascade structure. Sustainable metal‐free routes such as the Staudinger reaction or Schiff‐base

  据报道制备了新型的基于磷的大分子结构家族，称为“洋葱皮”磷纳米树突系统。该构建体基于使用几种结构单元的合成方法的多功能性，并基于这些系统在级联结构内进行区域选择性反应的能力。可持续的无金属路线，例如施陶丁格反应或席夫碱缩合，仅涉及水和氮作为副产物，可以使几种树枝状大分子在其骨架中带有多达七个不同的磷单元，每种都有特定的反应性。高度aurophilicPN的存在 PS片段使Au中选择性结扎我树枝状框架内。
• Dendrimers with N,N-Disubstituted Hydrazines as End Groups, Useful Precursors for the Synthesis of Water-Soluble Dendrimers Capped with Carbohydrate, Carboxylic or Boronic Acid Derivatives
  作者：Rosa-Marı́a Sebastián、Germinal Magro、Anne-Marie Caminade、Jean-Pierre Majoral

  DOI：10.1016/s0040-4020(00)00576-7

  日期：2000.8

  The first synthesis of dendrimers possessing N,N-disubstituted hydrazines as end groups allows us to carry out a versatile reactivity. Carbohydrate, carboxylic acid and boronic acid derivatives have been linked to the surface of the dendrimer in a very simple fashion, using the Schiff condensation. The stability of the resulting functionalized dendrimers has been checked: those linked to carboxylic

  具有N，N-二取代肼作为端基的树枝状聚合物的首次合成使我们能够进行多种反应。使用席夫缩合，以非常简单的方式将碳水化合物，羧酸和硼酸衍生物连接至树枝状聚合物的表面。已经检查了所得官能化树枝状聚合物的稳定性：与羧酸衍生物连接的那些在水中稳定超过7个月，证明了bonds键和树枝状聚合物的整个骨架都具有很高的稳定性。
• Phosphorylated Hydrazines and Aldehydes as Precursors of Phosphorus-Containing Multimacrocycles
  作者：Joeelle Mitjaville、Anne-Marie Caminade、Jean-Claude Daran、Bruno Donnadieu、Jean-Pierre Majoral

  DOI：10.1021/ja00111a007

  日期：1995.2

  afforded another type of bimacrocyclic species, 20, containing five phosphorus atoms. A Staudinger reaction between the phosphine 22 bearing a crown ether unit and the diazido tetraphosphorus-containing macrocycle 21 led to a trimacrocycle, 24, possessing one central phosphorus macrocycle and two crown ethers. Similarly the reaction between phosphine 22 (4 equiv) with the tetraazido tetraphosphorus-containing

  提供了另一种类型的双大环物质，20，含有五个磷原子。带有冠醚单元的膦 22 与含二叠氮基四磷的大环 21 之间的施陶丁格反应产生了三大环 24，它具有一个中心磷大环和两个冠醚。类似地，膦 22（4 当量）与含四叠氮基四磷的大环 25 之间的反应得到五大环物质 27。（1）R 3。双大环 15a、b 可以通过二醛 7 与三酰肼（Y）P[N 反应获得(CH3)- 具有一个中心磷大环和两个冠醚。类似地，膦 22（4 当量）与含四叠氮基四磷的大环 25 之间的反应得到五大环物质 27。（1）R 3。双大环 15a、b 可以通过二醛 7 与三酰肼（Y）P[N 反应获得( )- 具有一个中心磷大环和两个冠醚。类似地，膦 22（4 当量）与含四叠氮基四磷的大环 25 之间的反应得到五大环物质 27。（1）R 3。双大环 15a、b 可以通过二醛 7 与三酰肼（Y）P[N 反应获得( )-
• “Lego” Chemistry for the Straightforward Synthesis of Dendrimers
  作者：Valérie Maraval、Jaroslaw Pyzowski、Anne-Marie Caminade、Jean-Pierre Majoral

  DOI：10.1021/jo0344438

  日期：2003.7.1

  A new straightforward method of synthesis of dendrimers, using two branched monomers (CA(2) and DB2), is described. Each generation is obtained in a single quantitative step, with only N-2 or H2O as byproducts; generation 4 is obtained in only four steps. The end groups are alternatively phosphines and hydrazines; their versatile reactivity is illustrated by the reaction of generation 4 with a branched CD5 monomer, which increases the number of end groups in a single step from 48 to 250.
• Functionalized phosphorus derivatives of Salpen-like compounds: Synthesis and preliminary complexation studies
  作者：Alexandrine Maraval、Germinal Magro、Valérie Maraval、Laure Vendier、Anne-Marie Caminade、Jean-Pierre Majoral

  DOI：10.1016/j.jorganchem.2005.12.022

  日期：2006.3

  A new class of Salpen analogues based on phosphorus derivatives where the classical alkylene backbone has been replaced by a N-P-N linkage is described. Such linkage both affords it very good stability in water and an additional (fifth) potentially complexing site. The classical ortho-OH groups have been also replaced by various ortho-substituents, including diphenylphosphino groups. The synthesis of these compounds is easy and their structure can be varied at will at several levels. Several ways of synthesis can be used to combine the various fragments constituting these Salpen analogues. The structure of one of these fragments, an azide, was determined by X-ray crystallography. A preliminary Study of the complexation ability of some of these new ligands was carried out with groups 10 (Ni) and 11 (Au) elements. Depending on the type of substituents and the type of metals used, these compounds can act as mono-, or tetra-dentate ligands. (c) 2005 Elsevier B.V. All rights reserved.