硫酸可的松 | 912-25-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 中文名称: 硫酸可的松
• 中文别名: 2-甲基雌-4,9-二烯-3-酮-17-醇
• 英文名称: 17α,21-dihydroxy-4-pregnene-3,11,20-trione 21-sulfate
• 英文别名: 17,21-dihydroxy-4-pregnen-3,11,20-trione 21-sulfate；4-pregnen-17,21-diol-3,11,20-trione-21-sulfate；cortisone 21-sulfate；cortisone-21-sulfate；cortisone sulfate；17-Hydroxy-21-(sulfooxy)pregn-4-ene-3,11,20-trione；[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] hydrogen sulfate
• CAS: 912-25-4
• 化学式: C₂₁H₂₈O₈S
• 分子量: 440.515
• InChiKey: IWIJFUQFXLWZIA-ZPOLXVRWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  143
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  可的松 在 三氧化硫 、 三乙胺 作用下， 生成 硫酸可的松
  参考文献：
  名称：

  类固醇共轭物IV。用三乙胺-三氧化硫制备甾族硫酸盐。

  摘要：

  DOI：

  10.1016/s0039-128x(68)80079-0

文献信息

• BIOLOGICAL NASAL BRIDGE IMPLANT AND METHOD OF MANUFACTURE
  申请人：Grandhope Biotech Co., Ltd.

  公开号：EP2320966A1

  公开（公告）日：2011-05-18
• Prosthesis for joint cartilage repair and method of manufacture
  申请人：Xu Guo-Feng

  公开号：US20100021521A1

  公开（公告）日：2010-01-28

  A cartilage prosthesis is made according to a method that includes the steps of collecting animal material from a bovine, ovine or porcine source, the animal material being a cartilage, shaping the animal material to provide a desired shape for the cartilage implant, removing cells from the animal material, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.
• Biological nasal bridge implant and method of manufacturing
  申请人：Xu Guo-Feng

  公开号：US20100023124A1

  公开（公告）日：2010-01-28

  A nasal bridge implant is made according to a method that includes the steps of collecting animal material from a bovine or porcine source, the animal material being either a tendon or a ligament, removing cells from the animal material, shaping the animal material to provide a desired shape for the nasal bridge implant, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.
• Prosthesis for Joint Cartilage Repair and Method of Manufacture
  申请人：Xu Guo-Feng

  公开号：US20120135924A1

  公开（公告）日：2012-05-31

  A cartilage prosthesis is made according to a method that includes the steps of collecting animal material from a bovine, ovine or porcine source, the animal material being a cartilage, shaping the animal material to provide a desired shape for the cartilage implant, removing cells from the animal material, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.
• Biological nasal bridge implant and method of manufacture
  申请人：Xu Guo-Feng

  公开号：US20120128785A1

  公开（公告）日：2012-05-24

  A nasal bridge implant is made according to a method that includes the steps of collecting animal material from a bovine or porcine source, the animal material being either a tendon or a ligament, removing cells from the animal material, shaping the animal material to provide a desired shape for the nasal bridge implant, crosslinking the animal material, removing antigens from the animal material, subjecting the animal material to an alkaline treatment, coupling into the animal material active substances which are capable of adhering growth factor and stem cell, and packing the animal material in a container that contains a sterilization solution.