4-(N,N-二甲基氨基磺酰)-7-哌嗪苯并氧杂恶二唑 | 139332-64-2

• 物质功能分类: 分析化学 - 液相色谱 - HPLC标记试剂
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 中文名称: 4-(N,N-二甲基氨基磺酰)-7-哌嗪苯并氧杂恶二唑
• 中文别名: 4-(N,N-二甲氨基磺酰基)-7-哌嗪-2,1,3-苯并恶二唑；4-(N,N-二甲氨基磺酰基)-7-哌嗪-2,1,3-苯并恶二唑[用于高效液相色谱标记]
• 英文名称: 4-(N,N-Dimethylaminosulfonyl)- 7-Piperazino-2,1,3- Benzoxadiazole
• 英文别名: 4-(N,N-Dimethylsulfamoyl)-7-piperazino-benzofurazan；N,N-dimethyl-7-piperazin-1-yl-2,1,3-benzoxadiazole-4-sulfonamide
• CAS: 139332-64-2
• 化学式: C₁₂H₁₇N₅O₃S
• 分子量: 311.365
• InChiKey: XFQLOSBBYVMBGT-UHFFFAOYSA-N

物化性质

• 熔点：
  121.0 to 125.0 °C
• 沸点：
  513.5±60.0 °C(Predicted)
• 密度：
  1.373±0.06 g/cm3(Predicted)
• 稳定性/保质期：
  如果按照规格使用和储存，则不会发生分解，也不存在已知的危险反应。

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  100
• 氢给体数：
  1
• 氢受体数：
  8

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  2935009090

反应信息

• 作为反应物：
  描述：

  4-(N,N-二甲基氨基磺酰)-7-哌嗪苯并氧杂恶二唑 、 9,14,18-tris(tert-butoxycarbonyl)-2,2-dimethyl-4-oxo-3-oxa-5,9,14,18-tetraazaicosan-20-oic acid 在 O‐(1H‐benzotriazol‐1‐yl)‐N,N,N′,N′‐tetramethyluronium tetrafluoroborate 作用下， 以 乙腈 为溶剂， 以52%的产率得到tert-butyl (3-((tert-butoxycarbonyl)(2-(4-(7-(N,N-dimethylsulfamoyl)benzo[c][1,2,5]oxadiazol-4-yl)piperazin-1-yl)-2-oxoethyl)amino)propyl)(4-((tert-butoxycarbonyl)(3-((tert-butoxycarbonyl)amino)propyl)amino)butyl)carbamate
  参考文献：
  名称：

  Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system

  摘要：

  The synthesis of a series of conjugated spermine derivatives with benzoxadiazole, phenylxanthene or bodipy fluorophores is described. These fluorescent probes were used to identify the activity of the polyamine transport system (PTS). N-1-Methylspermine NBD conjugate 5 proved to have the optimal fluorescence characteristics and was used to show a selectivity for PTS-proficient CHO versus PTS-deficient CHO-MG cells. It can therefore be used as a tool for the selection of cells sensitive to cytotoxic compounds vectored through the PTS. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2009.03.052

文献信息

• METHOD AND SYSTEM FOR DETERMINING THE PRESENCE OF AN ODOROUS MATERIAL ON A FABRIC
  申请人：Henkel IP & Holding GmbH

  公开号：EP3751259A1

  公开（公告）日：2020-12-16

  A method for determining the presence of an odorous material on a fabric includes applying a benzofurazan indicator to the fabric, tagging the odorous material with the indicator, exposing the fabric to a light at a predefined wavelength to produce fluorescence of the tagged odorous material, and observing the fluorescence of the tagged odorous material through a bandpass filter. Also disclosed is a system including the fabric, the indicator applied to the fabric and configured to tag the odorous material, at least one light source arranged about the fabric and configured to direct light on the fabric to produce fluorescence of the tagged odorous material, and an imaging device arranged about the fabric to capture an image of the fabric through a bandpass filter with the image including at least one illuminated portion representing the tagged odorous material. Also disclosed is a method for determining the efficacy of a laundry product.

  一种确定织物上是否存在气味物质的方法包括：在织物上涂抹苯并呋喃指示剂，用指示剂标记气味物质，将织物暴露在预定波长的光线下以产生被标记气味物质的荧光，以及通过带通滤波器观察被标记气味物质的荧光。还公开了一种系统，包括织物、应用于织物并被配置为标记气味物质的指示剂、围绕织物布置并被配置为将光照射到织物上以产生标记气味物质荧光的至少一个光源，以及围绕织物布置以通过带通滤波器捕获织物图像的成像装置，图像包括代表标记气味物质的至少一个发光部分。还公开了一种确定洗衣产品功效的方法。
• NFC STABILIZED FOAM
  申请人：Cellutech AB

  公开号：EP2872244A1

  公开（公告）日：2015-05-20
• Sulfur-Containing Amino Acid Derivative
  申请人：AJINOMOTO CO., INC.

  公开号：US20130071863A1

  公开（公告）日：2013-03-21

  The present invention provides a method of measuring an endogenous low-molecular-weight compound specifically and conveniently with high sensitivity. Using the particular sulfur-containing amino acid derivative, a method of measuring an endogenous low-molecular-weight compound specifically and conveniently with high sensitivity can be provided.
• Method And System For Determining The Presence Of An Odorous Material On A Fabric
  申请人：Henkel IP & Holding GmbH

  公开号：US20200393381A1

  公开（公告）日：2020-12-17

  A method for determining the presence of an odorous material on a fabric includes applying a benzofurazan indicator to the fabric, tagging the odorous material with the indicator, exposing the fabric to a light at a predefined wavelength to produce fluorescence of the tagged odorous material, and observing the fluorescence of the tagged odorous material through a bandpass filter. Also disclosed is a system including the fabric, the indicator applied to the fabric and configured to tag the odorous material, at least one light source arranged about the fabric and configured to direct light on the fabric to produce fluorescence of the tagged odorous material, and an imaging device arranged about the fabric to capture an image of the fabric through a bandpass filter with the image including at least one illuminated portion representing the tagged odorous material. Also disclosed is a method for determining the efficacy of a laundry product.
• US9127039B2
  申请人：——

  公开号：US9127039B2

  公开（公告）日：2015-09-08

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