3β-hydroxy-5α-androstan-17-acetylhydrazone | 6387-92-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β-hydroxy-5α-androstan-17-acetylhydrazone
• CAS: 6387-92-4
• 化学式: C₂₁H₃₄N₂O₂
• 分子量: 346.513
• InChiKey: YUIJAVSKKMDLNQ-HGDYXINXSA-N

物化性质

• 密度：
  1.28±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  3β-hydroxy-5α-androstan-17-acetylhydrazone 在 劳森试剂 作用下， 以 甲苯 为溶剂， 反应 5.0h， 以68%的产率得到3β-mercapto-5α-androstan-17-thioacetylhydrazone
  参考文献：
  名称：

  Synthesis of biologically active steroid derivatives by the utility of Lawesson's reagent

  摘要：

  Steroid derivatives V, VI, VII and VIII reacted with Lawesson's reagent (LR) to produce spiro-oxazaphosphole-4', 17-androstene derivative XI, diazaphospholoandrostane XIV and the thionated derivatives XVI and XVII, respectively. The structures of the new compounds were confirmed by analytical and spectroscopic evidence. A mechanism accounting for the formation of the new compounds was given. The in vitro antimicrobial activity of the new compounds were tested. (c) 2005 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.steroids.2004.11.001
• 作为产物：
  描述：

  表雄酮 、 乙酰肼 生成 3β-hydroxy-5α-androstan-17-acetylhydrazone
  参考文献：
  名称：

  Elmegeed; Wardakhan, Egyptian Journal of Chemistry, 2005, vol. 48, # 4, p. 407 - 423

  摘要：

  DOI：