(1aR,3aR,3bS,5aR,6R,8aS,8bS,10aR)-6-((R)-1,5-Dimethyl-4-oxo-hexyl)-3a,5a-dimethyl-tetradecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-10-one | 104933-92-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (1aR,3aR,3bS,5aR,6R,8aS,8bS,10aR)-6-((R)-1,5-Dimethyl-4-oxo-hexyl)-3a,5a-dimethyl-tetradecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-10-one
• CAS: 104933-92-8
• 化学式: C₂₇H₄₂O₂
• 分子量: 398.629
• InChiKey: NBFPBTGCGOFIKM-DNDRFWHESA-N

反应信息

• 作为反应物：
  描述：

  (1aR,3aR,3bS,5aR,6R,8aS,8bS,10aR)-6-((R)-1,5-Dimethyl-4-oxo-hexyl)-3a,5a-dimethyl-tetradecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-10-one 在 吡啶溴化氢盐 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以70%的产率得到(5S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-4-oxo-hexyl)-10,13-dimethyl-1,4,5,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one
  参考文献：
  名称：

  A convenient isomerization of 6-oxo-3α,5-cyclo-5α-steroids to 6-oxo-Δ2-5α-steroids

  摘要：

  Direct isomerization of 6-oxo-3 alpha,5-cyclo-5 alpha-steroids to 6-oxo-delta 2-5 alpha-steroids was accomplished by pyridinium hydrobromide in dimethyl-formamide.

  DOI：

  10.1016/0039-128x(85)90020-0