[3-[2-[2-(2-Aminoethoxy)ethoxycarbonylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate | 159156-98-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: [3-[2-[2-(2-Aminoethoxy)ethoxycarbonylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
• CAS: 159156-98-6
• 化学式: C₄₆H₉₁N₂O₁₁P
• 分子量: 879.2
• InChiKey: BBJPYLDHKQBAQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12
• 重原子数：
  60
• 可旋转键数：
  50
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  182
• 氢给体数：
  3
• 氢受体数：
  12

文献信息

• Compounds and Methods for Targeted Immune System Delivery
  申请人：PAPPALARDO Juan Sabastian

  公开号：US20150238621A1

  公开（公告）日：2015-08-27

  Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.
• US9962448B2
  申请人：——

  公开号：US9962448B2

  公开（公告）日：2018-05-08