2-hydroxymethyl-3,4-dimethylphenol | 67730-47-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-hydroxymethyl-3,4-dimethylphenol
• 英文别名: 2-(Hydroxymethyl)-3,4-dimethylphenol
• CAS: 67730-47-6
• 化学式: C₉H₁₂O₂
• 分子量: 152.193
• InChiKey: UEAPSLDWNGSLHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-hydroxymethyl-3,4-dimethylphenol 、 环戊二烯 在 sodium periodate 作用下， 以 水 、 乙腈 为溶剂， 以50%的产率得到(1'S,2R,2'R,6'S,7'R)-1',10'-dimethylspiro[oxirane-2,9'-tricyclo[5.2.2.02,6]undeca-4,10-diene]-8'-one
  参考文献：
  名称：

  Molecular Complexity from Aromatics - An Efficient Route to 1,8-Dimethyl-5-spirocyclopropanetricyclo[6.3.0.0^²,6]undec-10-one: A Potential Intermediate for Synthesis of Ceratopicanol

  摘要：

  本文描述了一种从简单的芳香族前体中线性融合三萜烷中间体的新的立体选择性合成方法。环己-2,4-二烯酮的环加成反应和官能化三环癸烯酮的光化学氧杂二环庚烷重排反应是我们方法的关键特征。

  DOI：

  10.1055/s-2008-1078592

文献信息

• [EN] PROCESS FOR THE SYNTHESIS OF CUMENE HYDROPEROXIDE<br/>[FR] PROCÉDÉ DE SYNTHESE DE L'HYDROPEROXYDE DE CUMÈNE
  申请人：EUROTECNICA DEV & LICENSING S

  公开号：WO2003076381A1

  公开（公告）日：2003-09-18

  This invention refers to a process for the synthesis of cumene hydroperoxide and to the product thus obtained. More in particular, this invention refers to a process for the production of cumene hydroperoxide by oxidating cumene with oxygen, where this process is run in the presence of a basic medium insoluble in the reaction environment, and such as not to release inorganic cations to the reaction environment. Such a basic medium is preferably a pyridinic resin. The cumene hydroperoxide thus obtained, characterized by the fact of being free of inorganic cations, is a further object of the invention.

  本发明涉及一种合成叔丁基过氧化氢的方法，以及由此获得的产品。更具体地说，本发明涉及一种通过将叔丁基氧化为氧来生产叔丁基过氧化氢的方法，其中该过程在不溶于反应环境的碱性介质存在下进行，并且不会释放无机阳离子到反应环境中。这样的碱性介质最好是吡啶树脂。由此获得的叔丁基过氧化氢，其特点是不含无机阳离子，也是本发明的另一个对象。
• Improved cumene hydroperoxide concentration process
  申请人：Borealis AG

  公开号：EP2612849A1

  公开（公告）日：2013-07-10

  A process for the concentration of cumene hydroperoxide comprising: (I) transferring the reaction mixture from the oxidation of cumene to cumene hydroperoxide to the first of at least two concentration columns arranged in series; (II) distilling the reaction mixture in said concentration columns to increase the percentage of cumene hydroperoxide within the reaction mixture and removing cumene from the reaction mixture in each concentration column via an overhead stream; wherein at least the first of said concentration columns is provided with a fresh cumene feed.

  一种浓缩过氧化氢积苯的工艺，包括 (I) 将反应混合物中的积烯氧化成过氧化积烯的过程转移到至少两个串联排列的浓缩塔中的第一个； (II) 在所述浓缩塔中对反应混合物进行蒸馏，以增加反应混合物中过氧化氢积 苯的百分比，并通过顶流从每个浓缩塔中的反应混合物中除去积苯； 其中，至少第一个浓缩塔装有新进的积烯。
• Process for the synthesis of cumene hydroperoxide
  申请人：Codignola Franco

  公开号：US20060014985A1

  公开（公告）日：2006-01-19

  This invention refers to a process for the synthesis of cumene hydroperoxide and to the product thus obtained. More in particular, this invention refers to a process for the production of cumene hydroperoxide by oxidating cumene with oxygen, where this process is run in the presence of a basic medium insoluble in the reaction environment, and such as not to release inorganic cations to the reaction environment. Such a basic medium is preferably a pyridinic resin. The cumene hydroperoxide thus obtained, characterized by the fact of being free of inorganic cations, is a further object of the invention.

  本发明是指一种合成过氧化积苯的工艺和由此获得的产品。更具体地说，本发明是指一种通过用氧气氧化过氧化二甲苯来生产过氧化二甲苯的工艺，该工艺是在一种不溶于反应环境的碱性介质存在下进行的，这种碱性介质不会向反应环境释放无机阳离子。这种碱性介质最好是吡啶树脂。本发明的另一个目的是制得不含无机阳离子的过氧化氢积炭。
• DECOMPOSITION OF CUMENE HYDROPEROXIDE
  申请人：UOP LLC

  公开号：EP1922298A2

  公开（公告）日：2008-05-21
• US7141700B1
  申请人：——

  公开号：US7141700B1

  公开（公告）日：2006-11-28