2-<4-(1-Oxo-2-isoindolinyl)-phenyl>-propanal | 69433-37-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-<4-(1-Oxo-2-isoindolinyl)-phenyl>-propanal
• 英文别名: 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-I+/--methylbenzeneacetaldehyde；2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]propanal
• CAS: 69433-37-0
• 化学式: C₁₇H₁₅NO₂
• 分子量: 265.312
• InChiKey: NXCWWUMLCOQSLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• METHOD FOR ASYMMETRIC SYNTHESIS
  申请人：Jakel Christoph

  公开号：US20090326226A1

  公开（公告）日：2009-12-31

  The present invention relates to a process for asymmetric synthesis in the presence of a chiral catalyst comprising at least one complex of a metal of transition group VIII with ligands capable of dimerization via noncovalent bonds, such catalysts and their use.

  本发明涉及一种在手性催化剂的存在下进行不对称合成的过程，该催化剂包括至少一种过渡金属VIII族与能够通过非共价键二聚化的配体形成的配合物，以及这些催化剂及其用途。
• Improved metal-ligand complex catalyzed processes
  申请人：UNION CARBIDE CHEMICALS & PLASTICS

  公开号：EP1108707A1

  公开（公告）日：2001-06-20

  This invention relates to a person for separating one or more phosphorus acidic compounds from a reaction product fluid containing said one or more phosphorus acidic compounds, a metal-organophosphite ligand complex catalyst and optionally free organophosphite ligand which process comprises (a) treating said reaction product fluid with water sufficient to remove at least some amount of said one or more phosphorus acidic compounds from said reaction product fluid and (b) treating the water which contains phosphorus acidic compounds removed from said reaction product fluid with an acid removal substance sufficient to remove at least some amount of said one or more phosphorus acidic compounds from said water.

  本发明涉及一种从含有一种或多种磷酸性化合物的反应产物流体中分离一种或多种磷酸性化合物的方法、本发明涉及一种从含有一种或多种磷酸性化合物的反应产物流体中分离出一种或多种磷酸性化合物的工艺，该工艺包括：(a) 用足以从反应产物流体中去除至少一定量的所述一种或多种磷酸性化合物的水处理所述反应产物流体；(b) 用足以从所述水中去除至少一定量的所述一种或多种磷酸性化合物的脱酸物质处理从所述反应产物流体中去除的含有磷酸性化合物的水。
• Improved metal-ligand complex catalysed processes
  申请人：Union Carbide Chemical & Plastics Technology Corporation

  公开号：EP1764353A1

  公开（公告）日：2007-03-21

  A process for separating one or more cyclic products from a reaction product fluid comprising one or more cyclic reactants, a metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand, a non-polar solvent and said one or more cyclic products, wherein said process comprises: (1) reacting said one or more cyclic reactants in the presence of said metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand and non-polar solvent to form a multiphase reaction product fluid; and (2) separating said multiphase reaction product fluid to obtain a non-polar phase comprising said one or more cyclic reactants, metal-organophosphorus ligand complex catalyst, optionally free organophosphorus ligand and non-polar solvent and a polar phase comprising said one or more cyclic products.

  一种从包含一种或多种环状反应物、金属有机磷配体络合催化剂、可选游离有机磷配体、非极性溶剂和所述一种或多种环状产物的反应产物流体中分离一种或多种环状产物的工艺，其中所述工艺包括：(1) 在所述金属-有机磷配体络合催化剂、可选游离有机磷配体和非极性溶剂存在下，使所述一种或多种环状反应物发生反应，以形成多相反应产物流体；以及 (2) 分离所述多相反应产物流体，以获得包含所述一种或多种环状反应物、金属-有机磷配体络合催化剂、可选游离有机磷配体和非极性溶剂的非极性相，以及包含所述一种或多种环状产物的极性相。
• Hydroformylation process
  申请人：Dow Technology Investments LLC

  公开号：US10981851B2

  公开（公告）日：2021-04-20

  Some embodiments of the present invention relate to processes for reducing heavies formation in a solution comprising one or more aldehydes, such as a reaction fluid in a hydroformylation process. In some embodiments, the process comprises providing 0.1 to 5 wt. percent of an organic nitrogen compound based on the total weight of the aldehyde solution, the organic nitrogen compound comprising: wherein each of R1-R5 are independently hydrogen, an alkyl, or an aryl radical.

  本发明的一些实施方案涉及在包含一种或多种醛的溶液（如加氢甲酰化过程中的反应液）中减少重物形成的工艺。在一些实施方案中，该工艺包括提供基于醛溶液总重量 0.1 至 5 重量百分比的有机氮化合物，该有机氮化合物包括： 其中 R1-R5 中的每一个都独立地为氢、烷基或芳基。
• Dendritic macromolecules for metal-ligand catalyzed processes
  申请人：——

  公开号：US20020111438A1

  公开（公告）日：2002-08-15

  This invention relates to dendritic macromolecules and their use in metal-dendritic macroligand complex catalyzed processes, e.g., hydroformylation. The use of metal-dendritic macroligand complex catalysts in such processes facilitates the separation of desired product from catalyst, for example, by membrane filtration.

  本发明涉及树枝状大分子及其在金属-树枝状大配位体络合物催化过程（如加氢甲酰化）中的应用。在此类工艺中使用金属树枝状大配位体络合物催化剂，有利于通过膜过滤等方法将所需产物从催化剂中分离出来。