11,11-bis-(1H-indol-3-yl)-7-methyl-11H-indeno[1,2-b]quinoxaline | 1526911-59-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 11,11-bis-(1H-indol-3-yl)-7-methyl-11H-indeno[1,2-b]quinoxaline
• CAS: 1526911-59-0
• 化学式: C₃₂H₂₂N₄
• 分子量: 462.553
• InChiKey: YMMPBTSFGKVZCO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.26
• 重原子数：
  36.0
• 可旋转键数：
  2.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  57.36
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  吲哚 、 1,2,3-茚满三酮 、 3,4-二氨基甲苯 在 poly(N,N′-dibromo-N-ethylnaphthyl-2,7-disulfonamide 作用下， 以 neat (no solvent) 为溶剂， 反应 0.1h， 以94%的产率得到11,11-bis-(1H-indol-3-yl)-7-methyl-11H-indeno[1,2-b]quinoxaline
  参考文献：
  名称：

  Synthesis of Bisindolylindeno[1,2-b]quinoxaline and Bisindolylindeno[3,4-b]pyrazine with Poly(N,N′-dibromo-N-ethylnaphthyl-2,7-disulfonamide)

  摘要：

  Poly(N,N-dibromo-N-ethylnaphthyl-2,7-disulfonamide) (PBNS) as novel reagent was synthesized. Bisindolylindeno[1,2-b]quinoxaline and bisindolylindeno[3,4-b]pyrazine derivatives were synthesized in a simple and efficient method from the three-component condensation reaction of indole, indane-1,2,3-trione, and diamine aromatic compounds by PBNS under solvent-free conditions at 80 degrees C in good to excellent yields, short reaction times, and a simple procedure for new derivatives. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications((R)) for the following free supplemental resource(s): Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2013.829237