6,9,15,18-tetrahydro-7,16-methanodifluoreno[2,3-b:20,30-f][1,5]diazocine | 1193457-03-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 6,9,15,18-tetrahydro-7,16-methanodifluoreno[2,3-b:20,30-f][1,5]diazocine
• 英文别名: 1,16-Diazaoctacyclo[14.14.1.02,14.04,12.06,11.017,29.019,27.021,26]hentriaconta-2(14),3,6,8,10,12,17(29),18,21,23,25,27-dodecaene；1,16-diazaoctacyclo[14.14.1.02,14.04,12.06,11.017,29.019,27.021,26]hentriaconta-2(14),3,6,8,10,12,17(29),18,21,23,25,27-dodecaene
• CAS: 1193457-03-2；1193457-04-3；1193457-05-4
• 化学式: C₂₉H₂₂N₂
• 分子量: 398.507
• InChiKey: BYCDAZJFGJWOAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  31
• 可旋转键数：
  0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 2-氨基芴 在 三氟乙酸 、 氨 作用下， 以 水 为溶剂， 反应 24.0h， 以25%的产率得到6,9,15,18-tetrahydro-7,16-methanodifluoreno[2,3-b:20,30-f][1,5]diazocine
  参考文献：
  名称：

  Enantioseparations of non-benzenoid and oligo-Tröger’s bases by HPLC on Whelk O1 column

  摘要：

  The separation of enantiomers of several 'bis- and tris-Troger's bases' by HPLC on commercially available chiral stationary phase Whelk O1 is described for the first time. The observed structure-enantioselectivity relationships are in agreement with the previously established molecular recognition model. For all 'bis- and tris-Troger's bases' studied, satisfactory to excellent enantioselectivities were observed. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.07.036

文献信息

• Enantioseparations of non-benzenoid and oligo-Tröger’s bases by HPLC on Whelk O1 column
  作者：Sergey Sergeyev、Sara Stas、Adrienne Remacle、Christophe M.L. Vande Velde、Bohumil Dolenský、Martin Havlík、Vladimír Král、Jan Čejka

  DOI：10.1016/j.tetasy.2009.07.036

  日期：2009.8

  The separation of enantiomers of several 'bis- and tris-Troger's bases' by HPLC on commercially available chiral stationary phase Whelk O1 is described for the first time. The observed structure-enantioselectivity relationships are in agreement with the previously established molecular recognition model. For all 'bis- and tris-Troger's bases' studied, satisfactory to excellent enantioselectivities were observed. (C) 2009 Elsevier Ltd. All rights reserved.