1-iododibenzo[b,d]furan-2-ol | 51079-04-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: 1-iododibenzo[b,d]furan-2-ol
• 英文别名: 1-iodo-2-hydroxydibenzofuran；1-iododibenzofuran-2-ol
• CAS: 51079-04-0
• 化学式: C₁₂H₇IO₂
• 分子量: 310.091
• InChiKey: XEUGSJMRLQWGLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  33.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-iododibenzo[b,d]furan-2-ol 在 tris-(dibenzylideneacetone)dipalladium(0) 、 三乙胺 、 sodium t-butanolate 、 2-二环己基磷-2,4,6-三异丙基联苯 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 3.0h， 生成
  参考文献：
  名称：

  KR2023/155059

  摘要：

  公开号：
• 作为产物：
  描述：

  Dibenzofuran-2-yl formate 在 盐酸 、 一氯化碘 、 溶剂黄146 、 potassium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 反应 26.0h， 生成 1-iododibenzo[b,d]furan-2-ol
  参考文献：
  名称：

  Design, synthesis and antitubercular evaluation of novel 2-substituted-3H-benzofuro benzofurans via palladium–copper catalysed Sonagashira coupling reaction

  摘要：

  A series of novel natural product like 2-substiuted-3H-benzofurobenzofurans designed by molecular hybridization were synthesized in very good yields. The key reactions involved in the synthesis are iodination of 2-dibenzofuranol using iodine monochloride followed by palladium-copper catalyzed Sonagashira-coupling of 1-iododibenzofuran-2-ol with various alkyl and aryl acetylenes. Among the all 10 new compounds screened for in vitro anti-mycobacterial activity against Mycobacterium tuberculosis H37Rv, 2-(4-methoxy-2-methyl phenyl)-3H-benzofuro[3,2-e]benzofuran (7c) was found to be most active with MIC 3.12 mu g/mL and has shown lower cytotoxicity with good therapeutic index. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2013.07.048

文献信息

• Heterocyclic compound and organic light-emitting device comprising same
  申请人：LG CHEM, LTD.

  公开号：US11201293B2

  公开（公告）日：2021-12-14

  The present specification relates to a heterocyclic compound of Chemical Formula 1, and an organic light emitting device including the same. The heterocyclic compound as a material of an organic material layer of the organic light emitting device provides enhanced efficiency, low driving voltage and enhanced lifetime properties.

  本规范涉及化学式1的杂环化合物，以及包括该化合物的有机发光器件。作为有机发光器件有机材料层的材料，该杂环化合物提供了增强的效率、低驱动电压和增强的寿命特性。
• 헤테로고리 화합물 및 이를 포함하는 유기 전자 소자
  申请人：LG CHEM, LTD. 주식회사 엘지화학(120010134563) Corp. No ▼ 110111-2207995BRN ▼107-81-98139

  公开号：KR20180048409A

  公开（公告）日：2018-05-10

  본 명세서는 화학식 1의 헤테로고리 화합물 및 이를 포함하는 유기 발광 소자에 관한 것이다.

  本规范涉及化学式1中的杂环化合物及其所包含的有机发光器件。
• HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
  申请人：LG CHEM, LTD.

  公开号：US20190152985A1

  公开（公告）日：2019-05-23

  The present invention relates to a cyclic compound having a novel structure and an organic light emitting device comprising the same. The cyclic compound of Chemical Formula 1 used in an organic material layer of the organic light emitting device provides improved driving voltage, light efficiency, and lifetime characteristics.

  本发明涉及一种具有新颖结构的环状化合物，以及包括该化合物的有机发光器件。化学式1中的环状化合物用于有机发光器件的有机材料层，可提供改进的驱动电压、光效率和寿命特性。
• NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
  申请人：LG CHEM, LTD.

  公开号：US20220056048A1

  公开（公告）日：2022-02-24

  Provided is a compound of Chemical Formula 1: wherein: A is a benzene ring: X1 and X2 are each independently O or S; Y1 to Y3 are each independently N or CH, provided that at least one of Y1 to Y3 is N; Ar1 and Ar2 are each independently a substituted or unsubstituted: C6-60 aryl or C2-60 heteroaryl containing at least one of N, O, and S; R1 to R3 are each independently hydrogen, deuterium, halogen, cyano, nitro, amino, or a substituted or unsubstituted: C1-60 alkyl, C3-60 cycloalkyl, C2-60 alkenyl, C6-60 aryl, or C2-60 heteroaryl containing at least one of N, O, and S; and R4 and R5 are each independently hydrogen, deuterium, halogen, cyano, nitro, amino, or a substituted or unsubstituted: C1-60 alkyl, C3-60 cycloalkyl, C2-60 alkenyl, C6-60 aryl, or C2-60 heteroaryl containing at least one of N, O, and S, and an organic light emitting device including the same.

  提供的是化学式1的化合物，其中：A是苯环；X1和X2各自独立地是O或S；Y1至Y3各自独立地是N或CH，但至少其中之一是N；Ar1和Ar2各自独立地是取代或未取代的C6-60芳基或C2-60含N、O和S的杂芳基；R1至R3各自独立地是氢、氘、卤素、氰基、硝基、氨基或取代或未取代的C1-60烷基、C3-60环烷基、C2-60烯基、C6-60芳基或C2-60含N、O和S的杂芳基；R4和R5各自独立地是氢、氘、卤素、氰基、硝基、氨基或取代或未取代的C1-60烷基、C3-60环烷基、C2-60烯基、C6-60芳基或C2-60含N、O和S的杂芳基，以及包括该化合物的有机发光器件。
• 화합물, 이를 포함하는 감광성 수지 조성물, 감광재, 컬러필터, 및 디스플레이 장치
  申请人：LG CHEM, LTD. 주식회사 엘지화학(120010134563) Corp. No ▼ 110111-2207995BRN ▼107-81-98139

  公开号：KR20190140747A

  公开（公告）日：2019-12-20

  본 명세서는 화학식 1로 표시되는 화합물 및 이를 포함하는 감광성 수지 조성물, 감광재, 컬러필터 및 디스플레이 장치를 제공한다.

  此规范提供了以化学式1表示的化合物及其包含的光敏树脂组合物、光敏材料、彩色滤光片和显示器件。