2-hydroxybenzyl dansyl cadaverine | 1279626-61-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-hydroxybenzyl dansyl cadaverine
• 英文别名: DNSCH；5-(dimethylamino)-N-[5-[(2-hydroxyphenyl)methylideneamino]pentyl]naphthalene-1-sulfonamide
• CAS: 1279626-61-7
• 化学式: C₂₄H₂₉N₃O₃S
• 分子量: 439.579
• InChiKey: RAKIZFZAMDPYLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  31
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  90.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  铁粉 、 2-hydroxybenzyl dansyl cadaverine 以 水 、 乙腈 为溶剂， 生成 [Fe(2-hydroxybenzyl dansyl cadaverine)](3+)
  参考文献：
  名称：

  Highly selective fluorescent chemosensor for Fe3+ imaging in living cells

  摘要：

  2-Hydroxybenzyl dansyl cadaverine (DNSCH) was designed as a fluorescent chemosensor for Fe3+. DNSCH exhibited significant FL quenching with increasing concentrations of Fe3+. The presence of 15 M equiv of Fe3+ significantly quenched the FL intensity of DNSCH. The binding constant of DNSCH towards Fe3+ was determined and found to be 1.5 +/- 0.4 x 10(-4) M-1. DNSCH was employed as an intracellular chemosensor for Fe3+. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2010.11.025
• 作为产物：
  描述：

  丹酰尸胺 、 水杨醛 反应 24.0h， 以81%的产率得到2-hydroxybenzyl dansyl cadaverine
  参考文献：
  名称：

  Highly selective fluorescent chemosensor for Fe3+ imaging in living cells

  摘要：

  2-Hydroxybenzyl dansyl cadaverine (DNSCH) was designed as a fluorescent chemosensor for Fe3+. DNSCH exhibited significant FL quenching with increasing concentrations of Fe3+. The presence of 15 M equiv of Fe3+ significantly quenched the FL intensity of DNSCH. The binding constant of DNSCH towards Fe3+ was determined and found to be 1.5 +/- 0.4 x 10(-4) M-1. DNSCH was employed as an intracellular chemosensor for Fe3+. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2010.11.025