4-hydroxy-1H-thieno<2,3-b;4,5-b>dipyridin-2-one | 145325-36-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩并吡啶类
• 英文名称: 4-hydroxy-1H-thieno<2,3-b;4,5-b>dipyridin-2-one
• 英文别名: 6-Hydroxy-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5,10,12-pentaen-4-one；6-hydroxy-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5,10,12-pentaen-4-one
• CAS: 145325-36-6
• 化学式: C₁₀H₆N₂O₂S
• 分子量: 218.236
• InChiKey: DPHPAFCRSNEAST-UHFFFAOYSA-N

物化性质

• 沸点：
  543.3±50.0 °C(Predicted)
• 密度：
  1.629±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  90.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-(3-amino-thieno<2,3-b>pyrid-2-yl)-3-oxo-butanoate 在 氨 作用下， 以 乙醇 为溶剂， 反应 2.0h， 生成 4-hydroxy-1H-thieno<2,3-b;4,5-b>dipyridin-2-one
  参考文献：
  名称：

  Novel Thienopyridines

  摘要：

  A number of novel thieno[2,3-b]pyridines were prepared from the reaction of 1 with unsaturated haloalkanes, and by the reaction of the amino ketones 9 and 10 with DMF dimethylacetal or triethyl orthoformate. The synthesis of novel thieno[2,3-c] and [3,2-c] pyridines, and a thieno[2,3-b;4,5-b']dipyridine are also reported.

  DOI：

  10.1002/prac.19923340606

文献信息

• Novel Thienopyridines
  作者：A. D. Dunn、R. Norrie

  DOI：10.1002/prac.19923340606

  日期：——

  A number of novel thieno[2,3-b]pyridines were prepared from the reaction of 1 with unsaturated haloalkanes, and by the reaction of the amino ketones 9 and 10 with DMF dimethylacetal or triethyl orthoformate. The synthesis of novel thieno[2,3-c] and [3,2-c] pyridines, and a thieno[2,3-b;4,5-b']dipyridine are also reported.