methyl 2-(tert-butoxy)-2-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)-3-(2-propylpyridin-4-yl)-6-(trifluoromethyl)phenyl]acetate | 1596367-26-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: methyl 2-(tert-butoxy)-2-[2-(3,4-dihydro-2H-1-benzopyran-6-yl)-3-(2-propylpyridin-4-yl)-6-(trifluoromethyl)phenyl]acetate
• 英文别名: methyl 2-[2-(3,4-dihydro-2H-chromen-6-yl)-3-(2-propylpyridin-4-yl)-6-(trifluoromethyl)phenyl]-2-[(2-methylpropan-2-yl)oxy]acetate
• CAS: 1596367-26-8
• 化学式: C₃₁H₃₄F₃NO₄
• 分子量: 541.61
• InChiKey: VIGDWDXNRXJGNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  39
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  57.6
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES<br/>[FR] INHIBITEURS DE RÉPLICATION VIRALE, LEUR PROCÉDÉ DE PRÉPARATION ET LEURS APPLICATIONS THÉRAPEUTIQUES
  申请人：BIODIM LAB

  公开号：WO2014057103A1

  公开（公告）日：2014-04-17

  Inhibitors of viral replication of formula (I), their process of preparation and their therapeutical uses. The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.

  抑制病毒复制的化合物（I）及其制备过程和治疗用途。本发明涉及化合物，其在治疗或预防病毒性疾病，包括HIV方面的用途。
• Inhibitors of Viral Replication, Their Process of Preparation and Their Therapeutical Uses
  申请人：LABORATOIRE BIODIM

  公开号：US20150274718A1

  公开（公告）日：2015-10-01

  Inhibitors of viral replication of formula (I), their process of preparation and their therapeutical uses. The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.

  公式（I）的病毒复制抑制剂，它们的制备过程及其治疗用途。本发明涉及化合物，其用于治疗或预防病毒性疾病，包括HIV。
• INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES
  申请人：HIVIH

  公开号：EP2906539B1

  公开（公告）日：2017-06-21
• US9475802B2
  申请人：——

  公开号：US9475802B2

  公开（公告）日：2016-10-25