2-(3-hydroxyphenyl)-3-(pyridin-2-yl)-1,3-thiazolidin-4-one | 1392140-10-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-(3-hydroxyphenyl)-3-(pyridin-2-yl)-1,3-thiazolidin-4-one
• CAS: 1392140-10-1
• 化学式: C₁₄H₁₂N₂O₂S
• 分子量: 272.327
• InChiKey: DOKPRUMUFBNLMH-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  、 巯基乙酸 在 三氟化硼 作用下， 以 甲醇 、 甲苯 为溶剂， 反应 0.42h， 生成 2-(3-hydroxyphenyl)-3-(pyridin-2-yl)-1,3-thiazolidin-4-one
  参考文献：
  名称：

  Ultrasonics promoted synthesis of thiazolidinones from 2-aminopyridine and 2-picolilamine

  摘要：

  The efficient multicomponent synthesis of thiazolidinones from the reaction of arenealdehydes, mercaptoacetic acid and 2-picolilamine or 2-aminopyridine under ultrasound irradiation are reported. The reaction with 2-aminopyridine needs a Lewis acid catalysis to afford the corresponding 2-aryl-3-(pyridin-2-yl)-1,3-thiazolidin-4-ones. All novel compounds were identified and characterized by H-1 and C-13 NMR spectra. Applying the sonochemical methodology, two series of heterocyclic thiazolidinones were synthesized in good yields after short reaction times. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ultsonch.2012.03.004