(2-acryloyloxyethyl)dimethyldodecylammonium bromide | 150956-26-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (2-acryloyloxyethyl)dimethyldodecylammonium bromide
• 英文别名: propenoyloxyethyldimethyldodecanylammonium bromide；(2-Acryloyloxyethyl)dodecyldimethyl ammoniumbromide；dodecyl-dimethyl-(2-prop-2-enoyloxyethyl)azanium;bromide
• CAS: 150956-26-6
• 化学式: Br*C₁₉H₃₈NO₂
• 分子量: 392.42
• InChiKey: MFEOCVXPDXJAAC-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.72
• 重原子数：
  23
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  丙烯酸二甲胺基乙酯 、 溴代十二烷 在 对苯二酚 作用下， 反应 12.0h， 生成 (2-acryloyloxyethyl)dimethyldodecylammonium bromide
  参考文献：
  名称：

  Synthesis and antimicrobial properties of polymerizable quaternary ammoniums

  摘要：

  Introduction of biocide monomers during the process of polymerization is a promising approach in the development of new permanent non leaching biocide materials. Two series of surfactants monomers, with a quaternary ammonium group as polar head and an acrylic function as the polymerizable moiety, were synthesized and tested to evaluate their surface active properties alongside with their antibacterial and antifungal properties. Four microbial strains were used to perform the study: Pseudomonas aeruginosa, Staphylococcus aureus. Candida albicans and Aspergillus niger. The biocidal efficacy measured by bacterial and fungal growth inhibition expressed as MIC (Minimal Inhibitory Concentration) and MLC (Minimal Lethal Concentration) values was discussed as a function of molecular parameters. All the synthesized surfactant monomers presented bactericidal and fungicidal activities. Increasing the spacer between the acrylic part and the ammonium group has a favourable effect on the MIC and MLC results. (C) 2009 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2009.03.031

文献信息

• IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS
  申请人：Satake Kohsuke

  公开号：US20130202551A1

  公开（公告）日：2013-08-08

  An ionic compound capable of providing a cured material having superior antibacterial property and oxygen permeability, and a composition containing the ionic compound, and a cured material, a hydro gel and an ophthalmic lens which have long-term sustainable antibacterial property and superior oxygen permeability. The ionic compound is represented by the following formula (1): In formula (1), P represents a polymerizable functional group. Q + represents a cationic group: Z represents an n-valent siloxanyl group in which the total atomic weight of a group of constituent atoms is no less than 70 and no greater than 1,000; X m− represents an m-valent anion; and n is an integer of 1 to 10, where provided that n is no less than 2, a plurality of P3 and Q + 3 are each independently as defined above.

  一种离子化合物，能够提供具有优越抗菌性能和氧透性的固化材料，以及含有该离子化合物的组合物，以及具有长期可持续抗菌性能和优越氧透性的固化材料、水凝胶和眼镜片。该离子化合物由以下式（1）表示： 在式（1）中，P代表可聚合的功能基团。Q + 代表阳离子基团：Z代表一个n价硅氧烷基团，其中构成原子的总原子量不小于70且不大于1,000；X m− 代表m价阴离子；n为1至10的整数，其中n不小于2时，多个P3和Q + 3分别独立定义如上所述。
• CHOLESTEROL LEVEL DEPRESSANT
  申请人：HISAMITSU PHARMACEUTICAL CO. INC.

  公开号：EP0622078A1

  公开（公告）日：1994-11-02

  A cholesterol level depressant containing a non-cross-linking anion exchange resin having a structural unit represented by general formula (I) as the main ingredient, wherein R₁ represents benzyl or C₁-C₂₀ alkyl; R₂ and R₃ may be the same or different from each other and each represents C₁-C₄ alkyl; R₄ represents hydrogen or lower alkyl; X represents a physiologically acceptable counter ion; n is 1 to 3; and p represents an average degree of polymerization of 10 to 10,000.

  一种胆固醇水平抑制剂，含有一种非交联阴离子交换树脂，其主要成分具有通式 (I) 所代表的结构单元，其中 R₁ 代表苄基或 C₁-C₂₀ 烷基；R₂ 和 R₃ 可以相同或不同，各自代表 C₁-C₄ 烷基；R₄ 代表氢或低级烷基；X 代表生理学上可接受的反离子；n 为 1 至 3；p 代表 10 至 10,000 的平均聚合度。
• IONIC COMPOUND, COMPOSITION, CURED PRODUCT, HYDROGEL, AND OCULAR LENS
  申请人：Menicon Co., Ltd.

  公开号：EP2581394A1

  公开（公告）日：2013-04-17

  An object of the invention is to provide an ionic compound capable of providing a cured material having superior antibacterial property and oxygen permeability, and a composition containing the ionic compound, and to provide a cured material, a hydrogel and an ophthalmic lens which have long-term sustainable antibacterial property and superior oxygen permeability. The present invention provides the ionic compound represented by the following formula (1): in the formula (1), P represents a polymerizable functional group. Q+ represents a cationic group; Z represents an n-valent siloxanyl group in which the total atomic weight of a group of constituent atoms is no less than 70 and no greater than 1,000; Xm- represents an m-valent anion; and n is an integer of 1 to 10, where provided that n is no less than 2, a plurality of Ps and Q+s are each independently as defined above.

  本发明的目的是提供一种能够提供具有优异抗菌性和透氧性的固化材料的离子化合物，以及一种含有该离子化合物的组合物，并提供一种具有长期持续抗菌性和优异透氧性的固化材料、水凝胶和眼科透镜。本发明提供了由下式（1）代表的离子化合物： 式（1）中，P 代表可聚合官能团。Q+ 代表阳离子基团；Z 代表正价硅氧烷基团，其中一组组成原子的总原子量不小于 70 且不大于 1,000；Xm- 代表 m 价阴离子；n 为 1 至 10 的整数，其中只要 n 不小于 2，多个 Ps 和 Q+ 就各自独立地如上所定义。
• Non-crosslinked anion exchange resin and pharmaceutical composition containing same
  申请人：HISAMITSU PHARMACEUTICAL CO. INC.

  公开号：EP0835888B1

  公开（公告）日：2000-05-24
• STRENGTHENING RESINS AND PROCESSES FOR MAKING AND USING SAME
  申请人：ECOLAB USA INC.

  公开号：US20210079143A1

  公开（公告）日：2021-03-18

  Strengthening resins and processes for making and using same. In some embodiments, a resin mixture can include a solvent and a strengthening resin. The strengthening resin can include one or more hydrophobic monomers incorporated therein. The strengthening resin can have a chemical formula of (I). The chemical formula (I) can include: where each R 2 can be derived from a hydrophobic monomer.