1-Dimethylamino-5-hydroxynonan | 27384-62-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-Dimethylamino-5-hydroxynonan
• 英文别名: Dimethylamino-1-nonanol-5；1-Dimethylaminononanol(5)；1-(Dimethylamino)nonan-5-ol
• CAS: 27384-62-9
• 化学式: C₁₁H₂₅NO
• 分子量: 187.326
• InChiKey: BVBUDLALORKLJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  辛-1-炔-4-醇 在 镍 氢气 作用下， 生成 1-Dimethylamino-5-hydroxynonan
  参考文献：
  名称：

  Hasiak,B., Bulletin de la Societe Chimique de France, 1974, p. 2015 - 2022

  摘要：

  DOI：

文献信息

• Polivka,Z. et al., Collection of Czechoslovak Chemical Communications, 1970, vol. 35, p. 1131 - 1146
  作者：Polivka,Z. et al.

  DOI：——

  日期：——
• PHOSPHORAMIDITE SYNTHONES FOR THE SYNTHESIS OF SELF-NEUTRALIZING OLIGONUCLEOTIDE COMPOUNDS
  申请人：ZATA PHARMACEUTICALS, INC.

  公开号：US20170320902A1

  公开（公告）日：2017-11-09

  Compositions and compounds having nucleoside phosphoramidites, and methods of making the same are provided. The compounds can also have one or more amino groups that each can be positively charged. The compounds described permit facile attachment of certain neutralizing moieties with positive charges at their terminal ends on the backbones of oligonucleotides. The compounds can be used for the treatment of cancer, autoimmune, genetic and infectious diseases.