(17-Hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester | 134216-23-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (17-Hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester
• 英文别名: (2,5-Dioxopyrrolidin-1-yl) 2-[(17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl)oxy]acetate
• CAS: 134216-23-2
• 化学式: C₂₄H₂₉NO₆
• 分子量: 427.497
• InChiKey: AXIWBJDOAUTGCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  93.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (17-Hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester 、 [4-(2-aminoethyl)1,2-benzenediolato(2-)-O,O']bis(triphenylphosphine)platinum(II) 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 以53%的产率得到Pt(1,2-O2C6H3-4-(CH2)2NHCOCH2-3-O-estra-1,3,5(10)-triene-3,17β-diol)(PPh3)2
  参考文献：
  名称：

  Metalloimmunoassay. V. Steroid-Platinum(II)-o-catecholato complexes: A novel set of metallohaptens

  摘要：

  DOI：

  10.1016/s0020-1693(00)88557-6

文献信息

• [EN] MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS<br/>[FR] NANOPARTICULES DE SILICIUM MULTIFONCTIONNALISÉES, LEURS PROCÉDÉS DE PRÉPARATION ET LEURS UTILISATIONS DANS DES PROCÉDÉS DE DÉTECTION FONDÉS SUR L'ÉLECTROCHIMIOLUMINESCENCE
  申请人：ROCHE DIAGNOSTICS GMBH

  公开号：WO2018037060A1

  公开（公告）日：2018-03-01

  The present invention relates to novel multifunctionalized silicon nanopartides, to processes for their preparation and to compositions comprising the novel multifunctionalized silicon nanopartides. The invention also relates to the use of the novel multifunctionalized silicon nanopartides in electrochemiluminescence based detection methods and in the in vitro detection of an analyte. In particular, the invention relates to methods for measuring an analyte by in vitro methods employing the novel multifunctionalized silicon nanopartides.